CAS 854127-90-5

2-(4-Piperazinyl)-8-phenyl-4H-1-benzopyran-4-one dihydrochloride

Controlled Product

CAS: 854127-90-5

2-(4-Piperazinyl)-8-phenyl-4H-1-benzopyran-4-one dihydrochloride is an antibody that binds to the extracellular domain of the beta2 subunit of the nicotinic acetylcholine receptor. It is used as a research tool in cell biology, pharmacology, ligand binding studies and ion channel research. 2-(4-Piperazinyl)-8-phenyl-4H-1-benzopyran-4-one dihydrochloride has been shown to be an activator of voltage gated sodium channels and calcium channels in vitro. This molecule also interacts with receptors such as the muscarinic M3 receptor, alpha2A adrenergic receptors, and dopamine D2 receptors.

Formula: C₁₉H₂₀Cl₂N₂O₂

Purity: Min. 95%

Molecular weight: 379.3 g/mol

Ref: 3D-EJB12790

LY303511 hydrochloride

CAS: 854127-90-5

LY303511, a structural analog of LY294002, selectively inhibits mTOR-dependent phosphorylation of S6K, unlike its counterpart, which acts as a phosphatidylinositol 3-kinase (PI3K) inhibitor. It effectively reduces cell proliferation in human lung epithelial adenocarcinoma cells by hindering G2/M phase progression and suppressing casein kinase 2 activity. Additionally, LY303511 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sensitivity in HeLa cells resistant to TRAIL-induced apoptosis and blocks voltage-gated potassium (Kv) channels.

Formula: C₁₉H₂₀Cl₂N₂O₂

Color and Shape: Solid

Molecular weight: 379.28

Ref: TM-T84382