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CAS 85441-61-8

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Quinapril

Description:
Quinapril is an angiotensin-converting enzyme (ACE) inhibitor primarily used in the treatment of hypertension and heart failure. It is characterized by its ability to inhibit the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, thereby promoting vasodilation and reducing blood pressure. Quinapril is a white to off-white crystalline powder that is soluble in water and organic solvents. Its molecular formula is C19H24N2O5, and it has a molecular weight of approximately 344.41 g/mol. The compound is typically administered in the form of its hydrochloride salt, quinapril hydrochloride, which enhances its stability and bioavailability. Common side effects may include dizziness, fatigue, and cough, while serious adverse effects can involve renal impairment and angioedema. Quinapril is often prescribed in combination with other antihypertensive agents to achieve optimal blood pressure control. As with all medications, it is important for patients to follow their healthcare provider's instructions regarding dosage and administration.
Formula:C25H30N2O5
InChI:InChI=1S/C25H30N2O5/c1-3-32-25(31)21(14-13-18-9-5-4-6-10-18)26-17(2)23(28)27-16-20-12-8-7-11-19(20)15-22(27)24(29)30/h4-12,17,21-22,26H,3,13-16H2,1-2H3,(H,29,30)/t17-,21-,22-/m0/s1
InChI key:InChIKey=JSDRRTOADPPCHY-HSQYWUDLSA-N
SMILES:C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)(=O)N2[C@H](C(O)=O)CC=3C(C2)=CC=CC3
Synonyms:
  • (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid
  • 3-Isoquinolinecarboxylic acid, 2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-, [3S-[2[R*(R*)],3R*]]-
  • Ectren
  • Koretic
  • Quinapril
  • 3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-, (3S)-
  • Accupril
  • Asig
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Found 2 products.
  • Quinapril
    Glentham
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    Quinapril

    CAS:
    Formula:C25H30N2O5
    Molecular weight:438.52

    Ref: 7W-GP7064

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  • Quinapril
    Targetmol
    + Info

    Quinapril

    CAS:
    <p>Quinapril is an orally active, non-peptide, and non-thiol angiotensin-converting enzyme (ACE) inhibitor. It primarily blocks the conversion of angiotensin I to angiotensin II in both plasma and tissues. Upon enzymatic hydrolysis, Quinapril is converted into the pharmacologically active Quinaprilat and is effective in hypertension models.</p>
    Formula:C25H30N2O5
    Color and Shape:Solid
    Molecular weight:438.516

    Ref: TM-T204362