CAS 85474-76-6

2-Chloro-4-(1-piperazinyl)phenol

Description:

2-Chloro-4-(1-piperazinyl)phenol, with the CAS number 85474-76-6, is a chemical compound characterized by its phenolic structure, which includes a chlorine atom and a piperazine moiety. This compound typically appears as a solid or crystalline substance and is known for its potential biological activity, particularly in medicinal chemistry. The presence of the piperazine ring contributes to its pharmacological properties, making it of interest in the development of various therapeutic agents. The chlorine substituent on the phenolic ring can influence the compound's reactivity and solubility, affecting its interactions in biological systems. Additionally, 2-Chloro-4-(1-piperazinyl)phenol may exhibit antimicrobial or anti-inflammatory properties, although specific biological activities can vary based on the context of use. Safety data should be consulted for handling and exposure guidelines, as with any chemical substance. Overall, this compound represents a significant area of interest for researchers in both organic chemistry and pharmacology.

Formula: C₁₀H₁₃ClN₂O

InChI: InChI=1S/C10H13ClN2O/c11-9-7-8(1-2-10(9)14)13-5-3-12-4-6-13/h1-2,7,12,14H,3-6H2

InChI key: InChIKey=FXECOYYRPDGOQB-UHFFFAOYSA-N

SMILES: ClC=1C=C(C=CC1O)N2CCNCC2

Synonyms:

• Phenol, 2-chloro-4-(1-piperazinyl)-
• 2-Chloro-4-(1-piperazinyl)phenol
• 1-(3-Chloro-4-hydroxyphenyl)piperazine
• 2-Chloro-4-piperazin-1-ylphenol

2-Chloro-4-piperazin-1-ylphenol Dihydrochloride

Controlled Product

CAS: 85474-76-6

Applications A metabolite of Nefazodone (N389100), a novel antidepressant.
References Myol, R., et al.: Clin. Pharmacol. Ther., 37, 210 (1985), Haria, M., et al.: Drugs Aging, 4, 331 (1994), Kalgutkar, A., et al.: Drug Metab. Dispos., 33 243 (2005),

Formula: C₁₀H₁₃ClN₂O

Color and Shape: Neat

Molecular weight: 212.68

Ref: TR-C379665