CAS 854898-53-6

Rosuvastatin Impurity 2 Sodium Salt

CAS: 2125944-54-7, 854898-53-6

Formula: C₂₂H₂₇FN₃O₆S·Na

Color and Shape: Off-White Solid

Molecular weight: 480.53 22.99

Ref: 4Z-R-0937

(3R,5S)-5-[(S)-8-Fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl]-3,5-dihydroxypentanoic Acid Sodium Salt

Controlled Product

CAS: 854898-53-6

Applications (3R,5S)-5-[(S)-8-Fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl]-3,5-dihydroxypentanoic Acid is an impurity of the HMG-CoA reductase inhibitor Rosuvastatin (R700500).

Formula: C₂₂H₂₇FN₃NaO₆S

Color and Shape: Neat

Molecular weight: 503.52

Ref: TR-F592065

Rosuvastatin impurity B

CAS: 854898-53-6

Rosuvastatin impurity B is a hydrophilic impurity with a molecular weight of 716.8 that is found in the formulation of rosuvastatin. It is an analyte that can be detected by liquid chromatography and interacts with metformin, one of the analytes in the analysis. The calibration curve for this impurity was generated by adding ammonium formate to the mobile phase at different concentrations and measuring its interaction with rosuvastatin. The validation of this method was done by injecting samples containing known amounts of rosuvastatin impurity B and comparing the results to those obtained from the calibration curve. This method has a flow rate of 1 mL/min, which is sufficient for analyzing compounds that are eluted at low concentrations.

Formula: C₂₂H₂₇FN₃O₆S·Na

Purity: Min. 95%

Molecular weight: 503.52 g/mol

Ref: 3D-IR165403