CAS 85568-24-7

parathyroid hormone fragment human 1-44

Description:

Parathyroid hormone fragment human 1-44, with the CAS number 85568-24-7, is a peptide that represents a portion of the full-length parathyroid hormone (PTH), specifically comprising the first 44 amino acids of the molecule. This fragment retains biological activity and is primarily involved in calcium homeostasis and bone metabolism. PTH is secreted by the parathyroid glands and plays a crucial role in regulating serum calcium levels by promoting calcium release from bones, increasing renal tubular reabsorption of calcium, and stimulating the production of active vitamin D. The 1-44 fragment is often studied for its potential therapeutic applications in conditions such as osteoporosis and hypoparathyroidism. In terms of physical properties, this peptide is typically a white to off-white powder, soluble in water, and may require specific storage conditions to maintain stability. Its biological activity is closely linked to its structure, and research continues to explore its mechanisms and potential clinical uses.

Formula: C₂₂₅H₃₆₆N₆₈O₆₁S₂

Synonyms:

• pTH (1-44) (human)
• H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-Val-Ala-Leu-Gly-Ala-Pro-Leu-Ala-Pro-Arg-OH

pTH (1-44) (human)

CAS: 85568-24-7

Parathyroid Hormone (1-44), human

Formula: C₂₂₅H₃₆₆N₆₈O₆₁S₂

Molecular weight: 5063.93

Ref: 01-4014739

Parathyroid Hormone (Human, 1-44)

CAS: 85568-24-7

Amino acids 1-44 of the Parathyroid Hormone (PTH) which is a peptide hormone that is secreted from the parathyroid gland in the event of abnormal serum calcium levels and it ultimately regulates calcium and phosphate levels in the body. The PTH exerts its activity through binding to the G-protein coupled receptor type 1 PTH receptor, which activates adenylate cyclase or phospholipase C thus activating pathways involved in the mediation of bone resorption and bone formation. This product is suitable for life science applications and is available as a 0.5mg vial.

Formula: C₂₂₅H₃₆₆N₆₈O₆₁S₂

Purity: Min. 95%

Molecular weight: 5,063.9 g/mol

Ref: 3D-PTH-4094-V

pTH (1-44) (human)

CAS: 85568-24-7

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Formula: C₂₂₅H₃₆₆N₆₈O₆₁S₂

Purity: Min. 95%

Molecular weight: 5,063.87 g/mol

Ref: 3D-FP109372