CAS 85666-17-7

furegrelate sodium

Description:

Furegrelate sodium is a chemical compound primarily recognized for its role as a pharmacological agent. It is a sodium salt of furegrelate, which is a selective inhibitor of the enzyme lipoxygenase, involved in the metabolism of arachidonic acid. This inhibition can lead to reduced production of leukotrienes, which are inflammatory mediators, making furegrelate sodium potentially useful in treating conditions associated with inflammation. The compound is typically characterized by its solubility in water due to the presence of the sodium ion, which enhances its bioavailability. Furegrelate sodium is often studied for its therapeutic effects in cardiovascular diseases and other inflammatory disorders. Its safety profile and efficacy are evaluated through clinical studies, and it is important to consider its pharmacokinetics, including absorption, distribution, metabolism, and excretion, when assessing its potential applications in medicine. As with any pharmaceutical compound, understanding its mechanism of action and potential side effects is crucial for its effective use in clinical settings.

Formula: C₁₅H₁₀NNaO₃

InChI: InChI=1/C15H11NO3.Na/c17-15(18)14-8-12-7-10(3-4-13(12)19-14)6-11-2-1-5-16-9-11;/h1-5,7-9H,6H2,(H,17,18);/q;+1/p-1

SMILES: c1cc(Cc2ccc3c(c2)cc(C(=O)O)o3)cnc1.[Na]

Synonyms:

• Furegrelate
• 5-(3'-Pyridinylmethyl)benzofuran-2-carboxylate sodium
• Sodium 5-(3-pyridinylmethyl)-2-benzofurancarboxylate
• U 63557A
• 2-Benzofurancarboxylic acid, 5-(3-pyridinylmethyl)-, sodium salt
• Sodium 5-(Pyridin-3-Ylmethyl)-1-Benzofuran-2-Carboxylate

Furegrelate sodium

CAS: 85666-17-7

Furegrelate sodium

Purity: ≥98%

Molecular weight: 275.23g/mol

Ref: 54-BUP13559

Furegrelate sodium

CAS: 85666-17-7

Furegrelate sodium (U-63557A) is an orally active thromboxane synthase inhibitor with an IC50 of 15 nM in platelets.

Formula: C₁₅H₁₀NNaO₃

Purity: 99.92%

Color and Shape: Solid

Molecular weight: 275.23

Ref: TM-T11339