CAS 856676-23-8

Choline fenofibrate

Description:

Choline fenofibrate is a pharmaceutical compound that combines choline, a nutrient essential for various bodily functions, with fenofibrate, a lipid-regulating agent primarily used to treat hyperlipidemia. This compound is characterized by its ability to enhance lipid metabolism and reduce triglyceride levels in the bloodstream. Choline fenofibrate functions by activating peroxisome proliferator-activated receptors (PPARs), which play a crucial role in fatty acid oxidation and lipoprotein metabolism. The presence of choline in this compound may also contribute to its potential neuroprotective effects and support cognitive function. In terms of solubility, choline fenofibrate is generally more soluble in organic solvents than in water, which can influence its bioavailability and absorption in the body. The compound is typically administered in a controlled dosage form to ensure therapeutic efficacy while minimizing side effects. As with any medication, it is essential to consider potential interactions with other drugs and individual patient factors when prescribing choline fenofibrate.

Formula: C₂₂H₂₈ClNO₅

InChI: InChI=1/C17H15ClO4.C5H14NO/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11;1-6(2,3)4-5-7/h3-10H,1-2H3,(H,20,21);7H,4-5H2,1-3H3/q;+1/p-1

SMILES: CC(C)(C(=O)O)Oc1ccc(cc1)C(=O)c1ccc(cc1)Cl.CN(C)(C)CCO

Synonyms:

• 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid
• 2-Hydroxy-N,N,N-trimethylethanaminium 2-(-(4-chlorobenzoyl)phenoxy)-2- methylpropanoate
• Abt 335
• Fenofibrate de choline
• Trilipix
• Unii-4Bmh7Izt98
• Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 2-(4-(4- chlorobenzoyl)phenoxy)-2-methylpropanoic acid (1:1)
• 2-hydroxy-N,N,N-trimethylethanaminium 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate

Choline Fenofibrate (2-Hydroxy-N,N,N-trimethylethanaminium 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate)

CAS: 856676-23-8

Choline and its salts

Formula: C₁₇H₁₄ClO₄·C₅H₁₄NO

Color and Shape: White Powder

Molecular weight: 421.91 g/mol

Ref: 45-1133558

2-Hydroxy-N,N,N-Trimethylethanaminium 2-(4-(4-Chlorobenzoyl)Phenoxy)-2-Methylpropanoate

CAS: 856676-23-8

2-Hydroxy-N,N,N-Trimethylethanaminium 2-(4-(4-Chlorobenzoyl)Phenoxy)-2-Methylpropanoate

Purity: 98%

Molecular weight: 421.91g/mol

Ref: 54-OR1030349

Choline Fenofibrate

CAS: 856676-23-8

Choline Fenofibrate

Purity: ≥98%

Molecular weight: 421.91g/mol

Ref: 54-BUP10705

Choline Fenofibrate (CFRC-3)

CAS: 856676-23-8

Formula: C₁₇H₁₄ClO₄·C₅H₁₄NO

Color and Shape: White To Off-White Solid

Molecular weight: 317.75 104.17

Ref: 4Z-C-5910

Choline Fenofibrate

CAS: 856676-23-8

Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic

Formula: C₂₂H₂₈ClNO₅

Purity: 98.82%

Color and Shape: Solid

Molecular weight: 421.91

Ref: TM-T3941

Choline Fenofibrate

Controlled Product

CAS: 856676-23-8

Applications A new formulation of fenofibric acid, ABT-335, co-administered with statins.
References Athyros, V., et al.: Diabetes Care, 25, 1198 (2002), Sacks, F., et al.: Am. J. Cardiol., 90, 139 (2002), Wierzbicki, A., et al.: Curr. Med. Res. Opin., 19, 155 (2003), Sarwar, N., et al.: Circulation, 115, 450 (2007),

Formula: C₁₇H₁₄ClO₄·C₅H₁₄NO

Color and Shape: Neat

Molecular weight: 421.91

Ref: TR-C432665

Choline Fenofibrate-d6

Controlled Product

CAS: 856676-23-8

Applications Choline Fenofibrate-d6 is the labeled analogue of Choline Fenofibrate (C432665), a new formulation of fenofibric acid, ABT-335, co-administered with statins.
References Athyros, V., et al.: Diabetes Care, 25, 1198 (2002); Sacks, F., et al.: Am. J. Cardiol., 90, 139 (2002); Wierzbicki, A., et al.: Curr. Med. Res. Opin., 19, 155 (2003); Sarwar, N., et al.: Circulation, 115, 450 (2007)

Formula: C₁₇D₆H₈ClO₄·C₅H₁₄NO

Color and Shape: Neat

Molecular weight: 427.951

Ref: TR-C432667

Choline Fenofibrate

CAS: 856676-23-8

Formula: C₁₇H₁₄ClO₄C₅H₁₄NO

Molecular weight: 317.75 : 104.17

Ref: ST-EA-CP-F12010