CAS 856866-72-3

tedizolid

Description:

Tedizolid is an oxazolidinone antibiotic that is primarily used for the treatment of acute bacterial skin and skin structure infections. It exhibits a mechanism of action similar to that of linezolid, inhibiting bacterial protein synthesis by binding to the 50S ribosomal subunit. Tedizolid is effective against a range of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). One of its notable characteristics is its improved potency and pharmacokinetic profile, allowing for once-daily dosing. Tedizolid is also characterized by its favorable safety profile, with a lower incidence of certain side effects compared to older antibiotics in its class. It is administered orally or intravenously and is generally well-tolerated. The chemical structure of tedizolid includes a substituted oxazolidinone ring, contributing to its antibacterial activity. As with any antibiotic, the emergence of resistance is a concern, necessitating careful use and adherence to prescribed guidelines.

Formula: C₁₇H₁₅FN₆O₃

InChI: InChI=1S/C17H15FN6O3/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(9-25)27-17(24)26/h2-7,12,25H,8-9H2,1H3/t12-/m1/s1

InChI key: InChIKey=XFALPSLJIHVRKE-GFCCVEGCSA-N

SMILES: O=C1N(C[C@H](CO)O1)C2=CC(F)=C(C=C2)C=3C=CC(=NC3)C4=NN(C)N=N4

Synonyms:

• (5R)-3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone
• (5R)-3-[3-Fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one
• (R)-3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
• 2-Oxazolidinone, 3-[3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-, (5R)-
• 3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone
• Da 7157
• Sivextro
• Tedizolid Intermediate-8
• Torezolid
• Tr 700
• (5R)-3-{3-fluoro-4-[6-(2-Methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-5-(hydroxyMethyl)-1,3-oxazolidin-2-one Phosphate
• Tedizolid (TR-701)
• 3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone Torezolid (TR-701
• (R)-3-(3-Fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolid
• Specially acetazolaMide
• Tedizolid Impurity7
• Torezolid (TR-701
• Tedizolid free base
• -3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one
• 3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
• Tedizolid
• 3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidi
• (5R)-3-[3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-Oxazolidin
• (R)-3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one

Torezolid

CAS: 856866-72-3

Formula: C₁₇H₁₅FN₆O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 370.3378

Ref: IN-DA00G3Q0

Tedizolid

CAS: 856866-72-3

Tedizolid

Purity: ≥95%

Molecular weight: 370.34g/mol

Ref: 54-BUP09375

(R)-3-(3-Fluoro-4-(6-(2-Methyl-2H-Tetrazol-5-Yl)Pyridin-3-Yl)Phenyl)-5-(Hydroxymethyl)Oxazolidin-2-One

CAS: 856866-72-3

(R)-3-(3-Fluoro-4-(6-(2-Methyl-2H-Tetrazol-5-Yl)Pyridin-3-Yl)Phenyl)-5-(Hydroxymethyl)Oxazolidin-2-One

Purity: 98%

Molecular weight: 370.34g/mol

Ref: 54-PC109186

Torezolid

CAS: 856866-72-3

Formula: C₁₇H₁₅FN₆O₃

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to off-white or beige powder

Molecular weight: 370.34

Ref: 7W-GA5035

Tedizolid-13C-d3

CAS: 856866-72-3

Formula: C₁₆₁₃CH₁₂D₃FN₆O₃

Color and Shape: White To Off-White Solid

Molecular weight: 374.36

Ref: 4Z-T-163056

Tedizolid

CAS: 856866-72-3

Formula: C₁₇H₁₅FN₆O₃

Color and Shape: Off-White Solid

Molecular weight: 370.34

Ref: 4Z-T-163001

Tedizolid

CAS: 856866-72-3

Tedizolid (DA-7157)is a novel oxazolidinone-class antibiotic that inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit of

Formula: C₁₇H₁₅FN₆O₃

Purity: 96.97% - 99.89%

Color and Shape: Solid

Molecular weight: 370.34

Ref: TM-T1747

Tedizolid

CAS: 856866-72-3

Applications Tedizolid, known as TR-700, is an oral and i.v administered intracellular antibacterial drug.
References Schaadt, R. et al.: Antimicrob. Agents Chemother., 53, 3236 (2009); Lemaire, S. et al.: J. Antimicrob. Chemother., 64, 1035 (2009)

Formula: C₁₇H₁₅FN₆O₃

Color and Shape: Neat

Molecular weight: 370.34

Ref: TR-T013750

Torezolid

CAS: 856866-72-3

Torezolid (Tedizolid) is an oxazolidinone antibiotic with action on bacterial protein synthesis by binding to the 50S ribosomal subunit and is used for treating acute bacterial skin and skin structure infections.

Formula: C₁₇H₁₅FN₆O₃

Purity: Min. 95.0 Area-%

Color and Shape: Powder

Molecular weight: 370.34 g/mol

Ref: 3D-FT35374

TEDIZOLID

CAS: 856866-72-3

Formula: C₁₇H₁₅FN₆O₃

Purity: 98%

Molecular weight: 370.344

Ref: 10-F466765

Tedizolid-(d1,d2,d3) Deuterium Mixture

Controlled Product

CAS: 856866-72-3

Applications Tedizolid-d3, is the labelled form of Tedizolid, known as TR-700, is an oral and i.v administered intracellular antibacterial drug.
References Schaadt, R. et al.: Antimicrob. Agents Chemother., 53, 3236 (2009); Lemaire, S. et al.: J. Antimicrob. Chemother., 64, 1035 (2009)

Formula: C₁₇₂H₃H₁₂FN₆O₃

Color and Shape: Neat

Molecular weight: 373.36

Ref: TR-T013752