Stemonidine is a naturally occurring alkaloid derived from various plant species, particularly those in the genus *Stemonaceae*. It is characterized by its complex molecular structure, which includes multiple rings and functional groups that contribute to its biological activity. Stemonidine has garnered interest in pharmacology due to its potential effects on the central nervous system, including possible antinociceptive and neuroprotective properties. The compound exhibits a moderate level of solubility in organic solvents, while its solubility in water is limited, which can influence its bioavailability and therapeutic applications. Additionally, stemonidine's mechanism of action may involve interactions with neurotransmitter systems, although further research is needed to fully elucidate its pharmacodynamics. As with many alkaloids, safety and toxicity profiles are important considerations, and ongoing studies aim to better understand its effects and potential medicinal uses. Overall, stemonidine represents a fascinating subject of study within the field of natural products and medicinal chemistry.

This alkaloid occurs in the roots of Stemona japonica and behaves as a tertiary 
base. It has [α]
25
D
- 7.65°C and is characterized as the hydrochloride which 
decomposes at 2600 C and the methiodide, decomposing at 2480 C. The alkaloid is 
not affected by HCI in either AcOH or EtOH and the oxidation products formed 
with KMn04 depend upon the conditions. If the oxidation is carried out in 
Me2CO a base is obtained which yields a crystalline methiodide, m.p. 235°C. On 
the other hand, KMn04 in dilute H2 S04 at lOoC yields two substances (a) a 
neutral compound, C16H230sN, m.p. 208°C; [α]
D
- 58.30 which contains a 
lactone ring and one methoxyl group and (b) a substance CllH170 4N, m.p. 
202°C; [α]
D
- 24.17° which yields a semicarbazone, m.p. 258°C but contains 
no lactone group.
There is still ~ome doubt concerning the plant identity from which this alka_x0002_loid was isolated. Investigation by Suzuki suggested that it is not Stemona 
japonica as stated above but Stemona ovata Nakai.

STEMONIDINE

85700-47-6: Stemonidine is a naturally occurring alkaloid derived from various plant species, particularly those in the genus *Stemonaceae*. It is characterized by its complex molecular structure, which includes multiple rings and functional groups that contribute to its biological activity. Stemonidine has garnered interest in pharmacology due to its potential effects on the central nervous system, including possible antinociceptive and neuroprotective properties. The compound exhibits a moderate level of solubility in organic solvents, while its solubility in water is limited, which can influence its bioavailability and therapeutic applications. Additionally, stemonidine's mechanism of action may involve interactions with neurotransmitter systems, although further research is needed to fully elucidate its pharmacodynamics. As with many alkaloids, safety and toxicity profiles are important considerations, and ongoing studies aim to better understand its effects and potential medicinal uses. Overall, stemonidine represents a fascinating subject of study within the field of natural products and medicinal chemistry.

CAS 85700-47-6

STEMONIDINE