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CAS 857078-26-3

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N-Desmethyl Azithromycin B

Description:
N-Desmethyl Azithromycin B is a derivative of azithromycin, which is a macrolide antibiotic commonly used to treat various bacterial infections. This compound is characterized by the absence of a methyl group at the nitrogen atom in the azithromycin structure, which influences its pharmacological properties. N-Desmethyl Azithromycin B retains some antibacterial activity, although it may differ in potency and spectrum of action compared to its parent compound. The molecular structure typically includes a large lactone ring, multiple hydroxyl groups, and a nitrogen atom, contributing to its solubility and interaction with bacterial ribosomes. Its mechanism of action involves inhibiting protein synthesis in susceptible bacteria, making it effective against a range of pathogens. Additionally, the compound's stability, bioavailability, and metabolic profile can vary, impacting its therapeutic use. As with other macrolides, it may also exhibit side effects and interactions with other medications, necessitating careful consideration in clinical applications.
Formula:C37H70N2O11
Synonyms:
  • Azithromycin Impurity 45
  • N-Desmethyl Azithromycin B
  • (2R,3R,4S,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-4,10-dihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]ox
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Found 2 products.
  • N-Desmethyl Azithromycin B
    TRC
    + Info

    N-Desmethyl Azithromycin B

    Controlled Product
    CAS:
    <p>Applications N-Desmethyl Azithromycin B Is an impurity of Azithromycin (A927000), a semi-synthetic macrolide antibiotic, and related to Erythromycin A.<br>References Langtry, H.D., et al.: Drugs, 56, 273 (1998),<br></p>
    Formula:C37H70N2O11
    Color and Shape:Neat
    Molecular weight:718.95

    Ref: TR-D290805

    5mg
    2,845.00€
    500µg
    407.00€
    2500µg
    1,578.00€
  • N-Desmethyl azithromycin B
    Biosynth
    + Info

    N-Desmethyl azithromycin B

    CAS:
    <p>N-Desmethyl azithromycin B is a metabolite of the macrolide antibiotic azithromycin. It is an impurity in the drug product, and is present as an analytical standard for HPLC. N-Desmethyl azithromycin B can be found in the urine of patients taking azithromycin, but at much lower concentrations than the parent drug. This impurity is not toxicologically relevant, but may interfere with some analytical methods.</p>
    Formula:C37H70N2O11
    Purity:Min. 95%
    Molecular weight:718.96 g/mol

    Ref: 3D-ID137492

    1mg
    1,290.00€