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CAS 85721-05-7

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Zuclopenthixol acetate

Description:
Zuclopenthixol acetate is an antipsychotic medication primarily used in the treatment of schizophrenia and other psychotic disorders. It belongs to the thioxanthene class of antipsychotics and functions as a dopamine antagonist, which helps to alleviate symptoms such as hallucinations and delusions. The substance is characterized by its ability to block dopamine receptors in the brain, particularly the D2 subtype, which is associated with its therapeutic effects. Zuclopenthixol acetate is typically administered via intramuscular injection, providing a long-acting formulation that allows for less frequent dosing compared to oral antipsychotics. Its pharmacokinetics involve a relatively long half-life, contributing to sustained therapeutic effects. Common side effects may include sedation, extrapyramidal symptoms, and weight gain, which are typical of many antipsychotic medications. As with any medication, careful monitoring for adverse effects and interactions with other drugs is essential during treatment. Overall, Zuclopenthixol acetate is an important option in the management of severe psychiatric conditions.
Formula:C24H27ClN2O2S
InChI:InChI=1S/C24H27ClN2O2S/c1-18(28)29-16-15-27-13-11-26(12-14-27)10-4-6-20-21-5-2-3-7-23(21)30-24-9-8-19(25)17-22(20)24/h2-3,5-9,17H,4,10-16H2,1H3/b20-6-
InChI key:InChIKey=OXAUOBQMCDIVPQ-IOXNKQMXSA-N
SMILES:C(\CCN1CCN(CCOC(C)=O)CC1)=C/2\C=3C(SC=4C2=CC=CC4)=CC=C(Cl)C3
Synonyms:
  • Clopixol Acuphase
  • Clopenthixol acetate ester
  • 2-{4-[(3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]piperazin-1-yl}ethyl acetate
  • (Z)-4-(3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl)piperazine-1-ethyl acetate
  • Clopixol-Acuphase
  • 1-Piperazineethanol, 4-[(3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]-, 1-acetate
  • Zuclopenthixol acetate
  • 1-Piperazineethanol, 4-[(3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]-, acetate (ester)
  • 9H-Thioxanthene, 1-piperazineethanol deriv.
  • 1-Piperazineethanol, 4-[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]-, acetate (ester), (Z)-
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