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CAS 85737-04-8

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Guanosine 5′-(tetrahydrogen triphosphate), trilithium salt

Description:
Guanosine 5′-(tetrahydrogen triphosphate), trilithium salt, commonly referred to as trilithium guanosine triphosphate (GTP), is a nucleotide that plays a crucial role in cellular metabolism and signaling. It is characterized by its structure, which includes a guanine base, a ribose sugar, and a triphosphate group. The presence of lithium ions in the trilithium salt form enhances its solubility in aqueous solutions, making it useful in various biochemical applications. GTP is essential for protein synthesis, signal transduction, and as a substrate for RNA synthesis. Its triphosphate moiety is a high-energy component, providing energy for various cellular processes. In addition, GTP is involved in the regulation of G-proteins, which are pivotal in transmitting signals within cells. The compound is typically stable under physiological conditions but can be hydrolyzed in the presence of specific enzymes. Overall, trilithium guanosine triphosphate is a vital molecule in biochemistry, contributing to numerous metabolic pathways and cellular functions.
Formula:C10H16N5O14P3·3Li
InChI:InChI=1S/C10H16N5O14P3.3Li/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;;/t3-,5-,6-,9-;;;/m1.../s1
InChI key:InChIKey=DYIXNOPRTAXVIV-CYCLDIHTSA-N
SMILES:O[C@H]1[C@H](N2C3=C(N=C2)C(=O)N=C(N)N3)O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@H]1O.[Li]
Synonyms:
  • Guanosine 5′-(tetrahydrogen triphosphate), trilithium salt
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