CAS 85750-24-9

α-(4-Bromophenyl)-2-pyridineacetonitrile

Description:

α-(4-Bromophenyl)-2-pyridineacetonitrile, with the CAS number 85750-24-9, is an organic compound characterized by its unique structural features, which include a pyridine ring and a bromophenyl group. This compound typically appears as a solid or crystalline substance and is known for its potential applications in medicinal chemistry and as an intermediate in organic synthesis. The presence of the bromine atom enhances its reactivity, making it useful in various chemical reactions, including nucleophilic substitutions and coupling reactions. The nitrile functional group (-C≡N) contributes to its polarity and can influence its solubility in different solvents. Additionally, the compound may exhibit biological activity, which can be explored in pharmacological studies. Its synthesis generally involves the reaction of appropriate precursors under controlled conditions, and it is important to handle this compound with care due to the presence of bromine, which can pose health and environmental risks. Overall, α-(4-Bromophenyl)-2-pyridineacetonitrile is a significant compound in the field of organic chemistry with diverse applications.

Formula: C₁₃H₉BrN₂

InChI: InChI=1S/C13H9BrN2/c14-11-6-4-10(5-7-11)12(9-15)13-3-1-2-8-16-13/h1-8,12H

InChI key: InChIKey=PMKCUNAECONNCQ-UHFFFAOYSA-N

SMILES: C(C#N)(C1=CC=C(Br)C=C1)C2=CC=CC=N2

Synonyms:

• 2-(4-Bromophenyl)-2-(2-Pyridyl)Acetonitrile
• 2-(4-Bromophenyl)-2-(pyridin-2-yl)acetonitrile
• 2-(4-Bromophenyl)-2-pyridin-2-ylacetonitrile
• 2-Pyridineacetonitrile, α-(4-bromophenyl)-
• alpha-(4-Bromophenyl)pyridine-2-acetonitrile
• α-(4-Bromophenyl)-2-pyridineacetonitrile

Brompheniramine Impurity 3

CAS: 85750-24-9

Formula: C₁₃H₉BrN₂

Color and Shape: Yellow Solid

Molecular weight: 273.13

Ref: 4Z-B-160002

α-(4-Bromophenyl)-2-pyridineacetonitrile

Controlled Product

CAS: 85750-24-9

Applications α-(4-Bromophenyl)-2-pyridineacetonitrile, is an intermediate in the synthesis of Bromopheniramine Maleate, a derivative of Pheniramine (P297200), used to treat allergic conditions such as hay fever or urticaria.
References Dadkar, N.K. et al.: Psychopharmacology, 48, 7 (1976); Jancinova, V. et al.: Inflam. Res., 44, 183 (1997); Radke, R.S. et al.: Ind. Pharm., 8, 69 (2009);

Formula: C₁₃H₉BrN₂

Color and Shape: Neat

Molecular weight: 273.13

Ref: TR-B687195

Brompheniramine Impurity 1

CAS: 85750-24-9

Formula: C₁₃H₉BrN₂

Molecular weight: 273.13

Ref: ST-EA-CP-B52005