CAS: 858102-79-1 - 1,7-Diazaspiro[4.5]decan-2-one, 8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-, hydrochloride (1:1), (5S,8S)-

Formula: C₂₅H₂₆F₆N₂O₂·ClH

InChI: InChI=1S/C25H26F6N2O2.ClH/c1-16(17-11-19(24(26,27)28)13-20(12-17)25(29,30)31)35-15-23(18-5-3-2-4-6-18)10-9-22(14-32-23)8-7-21(34)33-22;/h2-6,11-13,16,32H,7-10,14-15H2,1H3,(H,33,34);1H/t16-,22-,23-;/m1./s1

InChI key: InChIKey=VEWAWEMXVUFANV-PVBCUUEWSA-N

SMILES: Cl.O=C1NC2(CNC(C=3C=CC=CC3)(COC(C=4C=C(C=C(C4)C(F)(F)F)C(F)(F)F)C)CC2)CC1

Synonyms:

• Sch 619734
• 1,7-Diazaspiro[4.5]decan-2-one, 8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-, hydrochloride (1:1), (5S,8S)-
• 1,7-Diazaspiro[4.5]decan-2-one, 8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-, monohydrochloride, (5S,8S)-
• Rolapitant hydrochloride

Rolapitant HCl

CAS: 552292-08-7 858102-79-1

• Formula: C₂₅H₂₆F₆N₂O₂·HCl
• Molecular weight: 500.49 36.46

Rolapitant Hydrochloride

CAS: 858102-79-1

Applications Rolapitant is an NK1 receptor antagonist that is used in the treatment of chemotherapy-induced …

• Formula: C₂₅H₂₆F₆N₂O₂·ClH
• Color and Shape: Neat
• Molecular weight: 536.94

Rolapitant hydrochloride

CAS: 858102-79-1

Rolapitant hydrochloride is a substance that belongs to the group of neurokinin-1 receptor antagonists. It …

• Formula: C₂₅H₂₇ClF₆N₂O₂
• Purity: Min. 95%
• Molecular weight: 536.9 g/mol

Rolapitant hydrochloride

CAS: 858102-79-1

Rolapitant HCl is a potent NK1 antagonist, non-CYP3A4 interactive, with anti-emetic effects and a Ki …

• Formula: C₂₅H₂₇ClF₆N₂O₂
• Purity: 98.35% - 99.79%
• Color and Shape: Solid
• Molecular weight: 536.94