CAS 85815-37-8

1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-5-[(glycylamino)methyl]-N,N-dimethyl-1H-1,2,4-triazole-3-carboxamide hydrochloride dihydrate

Description:

The chemical substance known as 1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-5-[(glycylamino)methyl]-N,N-dimethyl-1H-1,2,4-triazole-3-carboxamide hydrochloride dihydrate, with the CAS number 85815-37-8, is a complex organic compound characterized by its triazole core, which is a five-membered heterocyclic ring containing three nitrogen atoms. This compound features multiple functional groups, including a carboxamide and a chlorobenzoyl moiety, contributing to its potential biological activity. The presence of the hydrochloride salt form indicates enhanced solubility in aqueous environments, which is often beneficial for pharmacological applications. The dihydrate form suggests that the compound can incorporate water molecules into its crystalline structure, which may influence its stability and solubility. Overall, this substance is of interest in medicinal chemistry, particularly for its potential use in therapeutic applications, although specific biological activities and mechanisms would require further investigation.

Formula: C₂₁H₂₁Cl₃N₆O₃

InChI: InChI=1/C21H20Cl2N6O3.ClH.2H2O/c1-28(2)21(32)20-26-17(11-25-18(30)10-24)29(27-20)16-8-7-12(22)9-14(16)19(31)13-5-3-4-6-15(13)23;;;/h3-9H,10-11,24H2,1-2H3,(H,25,30);1H;2*1H2

InChI key: InChIKey=KHINGHZNENOVFD-UHFFFAOYSA-N

SMILES: C(NC(CN)=O)C=1N(N=C(C(N(C)C)=O)N1)C2=C(C(=O)C3=C(Cl)C=CC=C3)C=C(Cl)C=C2.Cl

Synonyms:

• 1H-1,2,4-Triazole-3-carboxamide, 5-[[(2-aminoacetyl)amino]methyl]-1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-N,N-dimethyl-, hydrochloride (1:1)
• 1H-1,2,4-Triazole-3-carboxamide, 5-[[(aminoacetyl)amino]methyl]-1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-N,N-dimethyl-, monohydrochloride
• 1H-1,2,4-triazole-3-carboxamide, 5-[[(2-aminoacetyl)amino]methyl]-1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-N,N-dimethyl-, hydrochloride, hydrate (1:1:2)
• 450191S
• Rilmazafone HCl
• Rilmazafone Hydrochloride
• 5-[[(2-aminoacetyl)amino]methyl]-1-[4-chloro-2-(2-chlorobenzoyl)phenyl]-N,N-dimethyl-1,2,4-triazole-3-carboxamide,hydrochloride

Rilmazafone hydrochloride

CAS: 85815-37-8

Formula: C₂₁H₂₁Cl₃N₆O₃

Molecular weight: 511.79

Ref: 7W-GP1026

Rilmazafone HCl

CAS: 85815-37-8

Formula: C₂₁H₂₀Cl₂N₆O₃·HCl

Molecular weight: 475.34 36.46

Ref: 4Z-R-086001

Rilmazafone Hydrochloride RS

CAS: 85815-37-8

Color and Shape: White To Pale Yellow-White Solid Crystalline Powder

Ref: 2K-1183500021

Rilmazafone Hydrochloride

CAS: 85815-37-8

Applications Rilmazafone Hydrochloride can be used in biological study of nitrazepam or rilmazafone hydrochloride combined with ethanol effects on human memory. It is also used as sleep aid medication.
References Suzuki, M., et al.: Neurosciences (Okayama, Japan), 20, 43 (1994)

Formula: C₂₁H₂₀Cl₂N₆O₃·HCl

Color and Shape: Neat

Molecular weight: 475.33 + (36.46)

Ref: TR-R509715

Rilmazafone hydrochloride

CAS: 85815-37-8

Rilmazafone hydrochloride is a potent inhibitor of the enzyme peptidyl-prolyl cis-trans isomerase A (PPIA). It binds to PPIA and prevents the formation of peptidyl-prolyl bonds in proteins. Rilmazafone hydrochloride is used as a research tool to study protein interactions, as an activator for peptides, and as a high purity reagent for life sciences. The active form of this drug binds to ligands on antibody molecules and blocks the activity of ion channels.

Formula: C₂₁H₂₁Cl₃N₆O₃

Purity: Min. 95%

Molecular weight: 511.8 g/mol

Ref: 3D-KDA81537