CAS 85862-86-8

Benzene, 1-azido-4-(methylsulfonyl)-

Description:

Benzene, 1-azido-4-(methylsulfonyl)-, also known by its CAS number 85862-86-8, is an organic compound characterized by the presence of an azido group (-N3) and a methylsulfonyl group (-SO2CH3) attached to a benzene ring. This compound features a benzene core, which is a stable aromatic hydrocarbon known for its resonance stability and ability to undergo electrophilic substitution reactions. The azido group is a notable feature, imparting potential reactivity, particularly in click chemistry and as a precursor for various nitrogen-containing compounds. The methylsulfonyl group contributes to the compound's solubility and polarity, enhancing its reactivity in nucleophilic substitution reactions. Benzene derivatives, including this compound, are often utilized in synthetic organic chemistry for the development of pharmaceuticals, agrochemicals, and materials science. Safety considerations are important, as azides can be sensitive and potentially explosive under certain conditions. Overall, Benzene, 1-azido-4-(methylsulfonyl)- is a versatile compound with significant implications in chemical synthesis and research.

Formula: C₇H₇N₃O₂S

1-Azido-4-methanesulfonylbenzene

CAS: 85862-86-8

1-Azido-4-methanesulfonylbenzene is a 1,3-dipolar cycloaddition agent that contains a heterocyclic ring. It inhibits the activity of the enzyme COX-2 (cyclooxygenase 2), which is the target for nonsteroidal anti-inflammatory drugs. 1-Azido-4-methanesulfonylbenzene has an inhibitory potency in the vicinal assay and has been shown to be a potent COX-2 inhibitor. The inhibition of COX-2 is thought to be due to its ability to bind with specificity to the heme group in the COX active site. This binding prevents substrate access and thus prevents prostaglandin synthesis.

Formula: C₇H₇N₃O₂S

Purity: Min. 95%

Molecular weight: 197.22 g/mol

Ref: 3D-KDA86286