CAS 859-07-4

Cephalosporin G

Description:

Cephalosporin G is a beta-lactam antibiotic that belongs to the cephalosporin class, which is derived from the fungus Acremonium. It is primarily used for its antibacterial properties, effective against a range of Gram-positive and some Gram-negative bacteria. The chemical structure of Cephalosporin G features a beta-lactam ring, which is crucial for its mechanism of action, as it inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. This leads to cell lysis and death of the bacteria. Cephalosporin G is characterized by its stability against certain beta-lactamases, although it may still be susceptible to others. It is typically administered via injection due to its poor oral bioavailability. The compound is also known for its relatively low toxicity in humans, making it a valuable option in treating various infections. However, like other antibiotics, its use should be guided by susceptibility testing to prevent the development of resistance.

Formula: C₁₈H₁₈N₂O₆S

InChI: InChI=1S/C18H18N2O6S/c1-10(21)26-8-12-9-27-17-14(16(23)20(17)15(12)18(24)25)19-13(22)7-11-5-3-2-4-6-11/h2-6,14,17H,7-9H2,1H3,(H,19,22)(H,24,25)/t14-,17-/m1/s1

InChI key: InChIKey=GOFCPYKUMJBHBH-RHSMWYFYSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(CC3=CC=CC=C3)=O)C2=O)(SCC1COC(C)=O)[H]

Synonyms:

• (6R,7R)-3-[(Acetyloxy)methyl]-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 3-(Acetoxymethyl)-8-oxo-7-(phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-(hydroxymethyl)-8-oxo-7-(2-phenylacetamido)-, acetate
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-(hydroxymethyl)-8-oxo-7-(2-phenylacetamido)-, acetate (ester)
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-8-oxo-7-[(2-phenylacetyl)amino]-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-8-oxo-7-[(phenylacetyl)amino]-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-8-oxo-7-[(phenylacetyl)amino]-, (6R-trans)-
• 7-(2-Phenylacetamido)cephalosporanic acid
• 7-(2-Phenylacetylamino)cephalosporanic acid
• 7-Phenylacetamidocephalosporanic acid
• Benzylcephalosporin
• Cepaloram
• Cephaloram
• Cephalosporin G
• Cephalosporin, (phenylmethyl)-
• Ro 11-7763

Cefaloram

CAS: 859-07-4

Formula: C₁₈H₁₈N₂O₆S

Molecular weight: 390.414

Ref: 7W-GA2877

Cefaloram

CAS: 859-07-4

Cefaloram is a cephalosporin antibiotic with action on bacterial cell wall synthesis and is used for treating bacterial infections.

Formula: C₁₈H₁₈N₂O₆S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 390.4 g/mol

Ref: 3D-AAA85907