CAS 85916-47-8
:katacalcin
Description:
Katacalcin, with the CAS number 85916-47-8, is a peptide that is derived from the calcitonin family of hormones. It is primarily known for its role in calcium homeostasis and bone metabolism. Katacalcin exhibits properties that can influence bone resorption and formation, making it of interest in the study of osteoporosis and other bone-related disorders. The substance is characterized by its ability to inhibit osteoclast activity, which are the cells responsible for bone resorption. This action contributes to the maintenance of bone density and overall skeletal health. Katacalcin is typically studied in the context of its potential therapeutic applications, particularly in conditions where bone density is compromised. Additionally, its structure and function are closely related to other calcitonin peptides, which share similar biological activities. As with many peptides, katacalcin's stability and bioavailability can be influenced by its formulation and delivery method, which are important considerations in its potential clinical use.
Formula:C97H154N34O36S2
InChI:InChI=1/C97H154N34O36S2/c1-43(2)29-55(119-83(154)60(36-72(143)144)123-86(157)62(39-132)127-87(158)63(40-133)126-79(150)52(21-27-168-7)113-75(146)48(98)32-70(139)140)81(152)115-51(18-20-69(137)138)77(148)114-49(13-9-23-108-96(102)103)76(147)122-59(35-71(141)142)84(155)120-56(30-46-37-106-41-110-46)82(153)117-53(14-10-24-109-97(104)105)93(163)130-25-12-16-65(130)89(160)124-57(31-47-38-107-42-111-47)85(156)128-73(44(3)4)90(161)129-92(167-6)91(162)118-54(22-28-169-8)94(164)131-26-11-15-64(131)88(159)116-50(17-19-66(99)134)78(149)121-58(33-67(100)135)80(151)112-45(5)74(145)125-61(95(165)166)34-68(101)136/h37-38,41-45,48-65,73,92,132-133H,9-36,39-40,98H2,1-8H3,(H2,99,134)(H2,100,135)(H2,101,136)(H,106,110)(H,107,111)(H,112,151)(H,113,146)(H,114,148)(H,115,152)(H,116,159)(H,117,153)(H,118,162)(H,119,154)(H,120,155)(H,121,149)(H,122,147)(H,123,157)(H,124,160)(H,125,145)(H,126,150)(H,127,158)(H,128,156)(H,129,161)(H,137,138)(H,139,140)(H,141,142)(H,143,144)(H,165,166)(H4,102,103,108)(H4,104,105,109)/t45-,48-,49?,50-,51?,52?,53-,54-,55?,56?,57-,58-,59?,60-,61-,62-,63?,64-,65-,73-,92-/m0/s1
SMILES:CC(C)CC(C(=NC(CCC(=O)O)C(=NC(CCCNC(=N)N)C(=NC(CC(=O)O)C(=NC(Cc1cnc[nH]1)C(=N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=N[C@@H](Cc1cnc[nH]1)C(=N[C@@H](C(C)C)C(=N[C@H](C(=N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=N[C@@H](CCC(=N)O)C(=N[C@@H](CC(=N)O)C(=N[C@@H](C)C(=N[C@@H](CC(=N)O)C(=O)O)O)O)O)O)O)OC)O)O)O)O)O)O)O)O)N=C([C@H](CC(=O)O)N=C([C@H](CO)N=C(C(CO)N=C(C(CCSC)N=C([C@H](CC(=O)O)N)O)O)O)O)O
Synonyms:- Calcitonin C-Terminal Flanking Peptide (human)
- H-Asp-Met-Ser-Ser-Asp-Leu-Glu-Arg-Asp-His-Arg-Pro-His-Val-Ser-Met-Pro-Gln-Asn-Ala-Asn-OH
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Found 4 products.
Calcitonin C-Terminal Flanking Peptide (human)
CAS:<p>Bachem ID: 4102089.</p>Formula:C97H154N34O36S2Purity:97.0%Color and Shape:WhiteMolecular weight:2436.63Calcitonin C-Terminal Flanking Peptide (human)
CAS:Katacalcin, a potent plasma calcium-lowering peptide, also called C-procalcitonin or PDN-21, flanks calcitonin on the C-terminal side within the human calcitonin precursor. Katacalcin specifically binds to the calcitonin receptor of CD14⁺ peripheral blood mononuclear cells.Formula:C97H154N34O36S2Purity:95.3%Color and Shape:White LyophilisateMolecular weight:2436.63Katacalcin
CAS:Katacalcin (PDN 21) is a potent plasma calcium-lowering peptide[1].Formula:C97H154N34O36S2Purity:98%Color and Shape:White PowderMolecular weight:2436.6
