CAS 85956-22-5

[(3S,7S,8S,8aR)-3-hydroxy-8-[2-[(2R)-4-hydroxy-6-oxo-tetrahydropyran-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate

Description:

The chemical substance with the name "[(3S,7S,8S,8aR)-3-hydroxy-8-[2-[(2R)-4-hydroxy-6-oxo-tetrahydropyran-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate" and CAS number 85956-22-5 is a complex organic compound characterized by its multi-ring structure and specific stereochemistry. It features a hexahydronaphthalene core, which contributes to its hydrophobic properties, along with hydroxyl and ester functional groups that enhance its solubility in polar solvents. The presence of a tetrahydropyran moiety indicates potential biological activity, as such structures are often found in natural products and pharmaceuticals. The stereochemical configuration, denoted by the (S) and (R) designations, suggests that the compound may exhibit specific interactions with biological targets, influencing its pharmacological profile. Overall, this compound's unique structural features and stereochemistry may contribute to its potential applications in medicinal chemistry or as a synthetic intermediate in organic synthesis.

Formula: C₂₃H₃₄O₆

InChI: InChI=1/C23H34O6/c1-4-13(2)23(27)29-20-11-16(24)9-15-6-5-14(3)19(22(15)20)8-7-18-10-17(25)12-21(26)28-18/h5-6,9,13-14,16-20,22,24-25H,4,7-8,10-12H2,1-3H3/t13-,14-,16+,17?,18+,19-,20?,22-/m0/s1

Pravastatin EP Impurity D (Pravastatin Lactone)

CAS: 85956-22-5

Formula: C₂₃H₃₄O₆

Color and Shape: White To Off-White Solid

Molecular weight: 406.52

Ref: 4Z-P-139

Pravastatin lactone

CAS: 85956-22-5

Pravastatin lactone, a non-enzymatic stomach derivative of pravastatin, inhibits HMG-CoA reductase and stems from mevastatin.

Formula: C₂₃H₃₄O₆

Color and Shape: Solid

Molecular weight: 406.519

Ref: TM-T37642

(1S,3S,7S,8S,8aR)-3-Hydroxy-8-[2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-Methylbutanoate (Pravastatin Lactone)

CAS: 85956-22-5

Color and Shape: Neat

Ref: 86-MM0503.04

Parecoxib Impurity 31

CAS: 85956-22-5

Formula: C₂₂H₂₃N₃O₇S₂

Color and Shape: White To Off-White Solid

Molecular weight: 505.56

Ref: 4Z-P-139035

Parecoxib Impurity 27

CAS: 85956-22-5

Formula: C₁₉H₁₈N₂O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 370.42

Ref: 4Z-P-139031

Pravastatin Lactone

Controlled Product

CAS: 85956-22-5

Stability Hygroscopic
Applications Pravastatin Lactone is a metabolite of Pravastatin (P702000).
References Boberg, M., et al.: Drug Metab. Dispos., 25, 321 (1997), Neuvonen, P., et al.: Clin. Pharmacol. Ther., 63, 332 (1998), Boyd, R., et al.: J. Clin. Pharmacol., 40, 91 (2000),

Formula: C₂₃H₃₄O₆

Color and Shape: Neat

Molecular weight: 406.51

Ref: TR-P701190

Pravastatin lactone

CAS: 85956-22-5

Pravastatin lactone is a prodrug of pravastatin that is hydrolyzed in vivo to its active form. It is used for the treatment of bowel disease and has been shown to have concentration-time curves that are linear and dose-dependent. Pravastatin lactone has an acidic pH, which may be due to the presence of carboxyl groups on the molecule. This drug also inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, which is an enzyme that catalyzes the conversion of HMG CoA to mevalonate in order to produce cholesterol. Pravastatin lactone also suppresses the production of fatty acids by inhibiting their synthesis at the level of acetyl-coenzyme A (acetyl-CoA). The drug has not shown any evidence of toxicity when administered to rats at doses up to 10 mg/kg body weight per day

Formula: C₂₃H₃₄O₆

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 406.51 g/mol

Ref: 3D-FP27124

Pravastatin-d9 δ-Valerolactone

Controlled Product

CAS: 85956-22-5

Formula: C₂₃D₉H₂₅O₆

Color and Shape: Neat

Molecular weight: 415.568

Ref: TR-P701191

Pravastatin EP Impurity D

CAS: 85956-22-5

Formula: C₂₃H₃₄O₆

Molecular weight: 406.52

Ref: ST-EA-CP-P52004