CAS 85977-49-7

Tauromustine

Description:

Tauromustine, with the CAS number 85977-49-7, is a synthetic compound that belongs to the class of alkylating agents, specifically designed for use in cancer therapy. It is a derivative of nitrogen mustard and is characterized by its ability to form covalent bonds with DNA, leading to cross-linking and subsequent disruption of DNA replication and transcription. This mechanism of action makes it effective against rapidly dividing cancer cells. Tauromustine is typically administered in a clinical setting and has been investigated for its potential in treating various malignancies. Its chemical structure includes a taurine moiety, which may influence its pharmacokinetics and toxicity profile. The compound is known to exhibit a range of side effects, common to many chemotherapeutic agents, including myelosuppression and gastrointestinal disturbances. Ongoing research aims to better understand its efficacy, optimal dosing regimens, and potential combination therapies to enhance its therapeutic outcomes while minimizing adverse effects.

Formula: C₇H₁₅ClN₄O₄S

InChI: InChI=1S/C7H15ClN4O4S/c1-11(2)17(15,16)6-4-9-7(13)12(10-14)5-3-8/h3-6H2,1-2H3,(H,9,13)

InChI key: InChIKey=RCLLNBVPCJDIPX-UHFFFAOYSA-N

SMILES: N(C(NCCS(N(C)C)(=O)=O)=O)(CCCl)N=O

Synonyms:

• 1-(2-Chloroethyl)-3-(2-(dimethylaminosulfonyl)ethyl)-1-nitrosourea
• 1-(2-Chloroethyl)-3-(2-(dimethylsulfamoyl)ethyl)-1-nitrosourea
• 2-((((2-Chloroethyl)nitrosoamino)carbonyl)amino)-N,N-dimethylethanesulfonamide
• 2-{[(2-chloroethyl)(nitroso)carbamoyl]amino}-N,N-dimethylethanesulfonamide
• Ccris 6346
• Ethanesulfonamide, 2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)-N,N-dimethyl-
• Ls-2667
• NSC 608678
• Tauromustina
• Tauromustina [INN-Spanish]
• Tauromustine [INN]
• Tauromustinum
• Tauromustinum [INN-Latin]
• Tcnu
• Unii-511F69K76Y

Tauromustine

CAS: 85977-49-7

Applications Tauromustine is a compound being used in the research of slow-release antitumor gel injections.
References Sun, Q., Sun, Z., Faming Zhuanli Shenqing (2009)

Formula: C₇H₁₅ClN₄O₄S

Color and Shape: Light Yellow

Molecular weight: 286.736

Ref: TR-T009125

Tauromustine

CAS: 85977-49-7

Tauromustine is an anticancer agent, which is a chemical derivative developed from mustards. It operates by targeting cellular DNA through two primary mechanisms: methylation and alkylation. These processes disrupt the DNA structure, impeding replication and transcription, which are crucial for tumor cell proliferation and survival. The compound's unique approach combines the properties inherent to methylating agents with those of classic alkylating compounds, offering a dual mechanism that enhances its antitumor efficacy.

Formula: C₇H₁₅ClN₄O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 286.74 g/mol

Ref: 3D-KDA97749