CAS 86-13-5: Benztropine

Description: Benztropine, with the CAS number 86-13-5, is a synthetic compound primarily used in the treatment of Parkinson's disease and drug-induced extrapyramidal symptoms. It is classified as an anticholinergic agent, which means it works by blocking the action of acetylcholine, a neurotransmitter involved in muscle control and coordination. The chemical structure of benztropine features a tropane ring fused to a benzene ring, contributing to its pharmacological properties. It is typically administered orally and has a moderate lipophilicity, allowing it to cross the blood-brain barrier effectively. Benztropine exhibits a relatively long half-life, which supports its use in managing symptoms over extended periods. Common side effects may include dry mouth, blurred vision, and constipation, reflecting its anticholinergic activity. Due to its potential for misuse, it is classified as a controlled substance in some jurisdictions. Overall, benztropine plays a significant role in neurology, particularly in managing movement disorders.

Formula: C₂₁H₂₅NO

InChI: InChI=1/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19+,20+

InChI key: InChIKey=GIJXKZJWITVLHI-PMOLBWCYNA-N

SMILES: O(C(C=1C=CC=CC1)C=2C=CC=CC2)C3CC4N(C)C(CC4)C3

Synonyms:

• UNII-1NHL2J4X8K
• 1-alpha-H,5-alpha-H-Tropane, 3-alpha-(diphenylmethoxy)-
• 8-Azabicyclo(3.2.1)octane, 3-(diphenylmethoxy)-8-methyl-, endo-
• 8-Azabicyclo[3.2.1]octane, 3-(diphenylmethoxy)-8-methyl-, (3-endo)-
• Benztropinum
• 8-Azabicyclo[3.2.1]octane, 3-(diphenylmethoxy)-8-methyl-, endo-
• NK 02
• Cobrentin
• (3-endo)-3-(Diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane
• Benztropine
• Cogentinol
• Akitan
• Cogentine
• Tropine benzohydryl ether
• Benzatropinum
• (1R,5R)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane
• 1alphaH,5alphaH-tropane, 3alpha-(diphenylmethoxy)-
• Benzatropinum [INN-Latin]
• Benzatropina
• HSDB 3014
• 1αH,5αH-Tropane, 3α-(diphenylmethoxy)-
• Benzatropina [INN-Spanish]

Benztropine Mesylate

CAS: 132-17-2 86-13-5

• Formula: C₂₁H₂₅NO·CH₄O₃S
• Purity: >98.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 403.54

Benzatropine

CAS: 86-13-5

Benzatropine: Central muscarinic blocker, inhibits dopamine uptake, treats Parkinson's symptoms.

• Formula: C₂₁H₂₅NO
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 307.43