CAS 86-35-1

Ethotoin

Description:

Ethotoin, with the CAS number 86-35-1, is a chemical compound primarily recognized for its use as an anticonvulsant medication. It is classified as a hydantoin derivative, similar in structure to phenytoin, and is utilized in the management of epilepsy. Ethotoin is characterized by its ability to stabilize neuronal membranes and reduce the frequency of seizures by modulating sodium channels in the brain. The compound is typically administered orally and is known for its relatively low toxicity compared to other anticonvulsants. Ethotoin is also notable for its pharmacokinetic properties, including its absorption, distribution, metabolism, and excretion, which can vary among individuals. While it has been effective for some patients, its use has declined in favor of newer anticonvulsants with improved safety profiles and efficacy. As with any medication, potential side effects may include dizziness, drowsiness, and gastrointestinal disturbances, necessitating careful monitoring during treatment.

Formula: C₁₁H₁₂N₂O₂

InChI: InChI=1/C11H12N2O2/c1-2-13-10(14)9(12-11(13)15)8-6-4-3-5-7-8/h3-7,9H,2H2,1H3,(H,12,15)

InChI key: InChIKey=SZQIFWWUIBRPBZ-UHFFFAOYSA-N

SMILES: O=C1C(NC(=O)N1CC)C2=CC=CC=C2

Synonyms:

• 1-Ethyl-2,5-dioxo-4-phenylimidazolidine
• 2,4-Imidazolidinedione, 3-ethyl-5-phenyl-
• 3-Ethyl-5-Phenylhydantoin
• 3-Ethyl-5-Phenylimidazolidine-2,4-Dione
• 3-Ethyl-5-phenyl-2,4-imidazolidinedione
• 3-Ethyl-5-phenyl-hydantoin
• 3-Ethyl-5-phenylimidazolidin-2,4-dione
• Ac-695
• Accenon
• Ethotoine
• Etotoina
• Hydantoin, 3-ethyl-5-phenyl-
• Peganone
• Pegoanone
• ETHOTOIN (200 MG)
• ETHOTOIN USP/EP/BP
• Ethotoin ((±)-Ethotoin)
• Hydantoin, 3-ethyl-5-phenyl- (6CI, 7CI, 8CI)
• 3-ethyl-5-phenyl-hydantoi
• Etbotoin
• ETHOTOIN

Ethotoin

CAS: 86-35-1

Hydantoin and its derivatives

Formula: C₁₁H₁₂N₂O₂

Color and Shape: Powder

Molecular weight: 204.08988

Ref: 45-1264501

Ethotoin

CAS: 86-35-1

Formula: C₁₁H₁₂N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 204.2252

Ref: IN-DA00GXZX

ETHOTOIN

CAS: 86-35-1

ETHOTOIN

Purity: ≥98%

Molecular weight: 204.23g/mol

Ref: 54-BUP06625

ETHOTOIN

CAS: 86-35-1

Ethotoin (Peganone), an orally active anticonvulsant agent utilized in epilepsy research, is a hydantoin derivative analogous to phenytoin [1].

Formula: C₁₁H₁₂N₂O₂

Purity: ≥98%

Color and Shape: Stout Prisms From Water Solid

Molecular weight: 204.23

Ref: TM-TD1228

Ethotoin

Controlled Product

CAS: 86-35-1

Applications Ethotoin is a hydantoin based anticonvulsant drug used in the treatment of epilepsy.
References Kesselheim, A.S., et al.: Drugs., 70, 605 (2010);

Formula: C₁₁H₁₂N₂O₂

Color and Shape: Neat

Molecular weight: 204.23

Ref: TR-E890535

Ethotoin

CAS: 86-35-1

Purity: 98%

Molecular weight: 204.2290039

Ref: 10-F600885

Ethotoin-d5

Controlled Product

CAS: 86-35-1

Applications Ethotoin-d5 is the labelled analogue of Ethotoin, a hydantoin based anticonvulsant drug used in the treatment of epilepsy.
References Kesselheim, A.S., et al.: Drugs., 70, 605 (2010);

Formula: C₁₁H₇D₅N₂O₂

Color and Shape: Neat

Molecular weight: 209.26

Ref: TR-E890537

Ethotoin-d5

CAS: 86-35-1

Ethotoin is a hydantoin antiepileptic drug. It acts by blocking the action of the sodium/potassium ATPase pump, which is important in maintaining the electrochemical gradient necessary for nerve cell repolarization and subsequent synaptic transmission. This leads to an increase in neuronal excitability and seizures, making it an effective antiepileptic drug. Ethotoin is also used to treat depression and other mental disorders. The uptake of ethotoin into nervous tissue can be inhibited by calcium ions, stabilizing membranes and preventing depolarization.

Formula: C₁₁H₇D₅N₂O₂

Purity: Min. 95%

Molecular weight: 209.26 g/mol

Ref: 3D-AAA08635