CAS 86-38-4

6,9-Dichloro-2-methoxyacridine

Description:

6,9-Dichloro-2-methoxyacridine is an organic compound belonging to the acridine family, characterized by its fused three-ring structure. It features two chlorine atoms at the 6 and 9 positions and a methoxy group at the 2 position, which contributes to its chemical reactivity and potential biological activity. This compound is typically a solid at room temperature and may exhibit a range of colors depending on its purity and form. It is known for its applications in various fields, including medicinal chemistry and dye production, due to its fluorescent properties. The presence of chlorine atoms enhances its lipophilicity, potentially influencing its interaction with biological membranes. Additionally, the methoxy group can affect its solubility and reactivity. Safety considerations are important when handling this compound, as it may pose health risks, including potential carcinogenicity. Proper laboratory protocols should be followed to mitigate exposure. Overall, 6,9-Dichloro-2-methoxyacridine is a compound of interest in both research and industrial applications.

Formula: C₁₄H₉Cl₂NO

InChI: InChI=1S/C14H9Cl2NO/c1-18-9-3-5-12-11(7-9)14(16)10-4-2-8(15)6-13(10)17-12/h2-7H,1H3

InChI key: InChIKey=RYRNQWYNHLLOGX-UHFFFAOYSA-N

SMILES: ClC=1C2=C(N=C3C1C=CC(Cl)=C3)C=CC(OC)=C2

Synonyms:

• 2-Methoxy-6,9-dichloroacridine
• 3,9-Dichloro-7-methoxyacridine
• Acridine, 6,9-dichloro-2-methoxy-
• Halocrin
• Halocrine
• NSC 2095
• NSC 2951
• 6,9-Dichloro-2-methoxyacridine

6,9-Dichloro-2-methoxyacridine, 98%

CAS: 86-38-4

6,9-Dichloro-2-methoxyacridine is used to prepare 6-chloro-2-methoxy-acridin-9-ylamine by reacting with phenol and ammonium carbonate. It is used in the preparation of 9-amino-6-chloro-2-methoxyacridine, N'-(6-Chloro-2-methoxy-acridin-9-yl)-heptylamine and N,N'-bis-(6-chloro-2-methoxy-acridin-9-yl)-

Formula: C₁₄H₉Cl₂NO

Purity: 98%

Color and Shape: Yellow to yellow-green, Powder

Molecular weight: 278.13

Ref: 02-L05913

6,9-Dichloro-2-methoxyacridine

CAS: 86-38-4

Formula: C₁₄H₉Cl₂NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 278.1334

Ref: IN-DA003N1N

6,9-Dichloro-2-methoxyacridine

CAS: 86-38-4

6,9-Dichloro-2-methoxyacridine

Purity: ≥95%

Color and Shape: Yellow Powder

Molecular weight: 278.13g/mol

Ref: 54-OR24945

6,9-Dichloro-2-methoxyacridine

CAS: 86-38-4

Purity: 97.0%

Color and Shape: Solid, No data available.

Molecular weight: 278.1300048828125

Ref: 10-F067659

6,9-Dichloro-2-methoxyacridine

CAS: 86-38-4

6,9-Dichloro-2-methoxyacridine (DCA) is a fluorescent probe that can be used to measure the cytosolic Ca2+ concentration in mammalian cells. DCA binds to chloride ions and emits a fluorescence signal proportional to the cytosolic Ca2+ concentration. The binding constants for DCA and chloride are low, which makes this probe an ideal candidate for measuring cytosolic Ca2+. DCA has been shown to inhibit cancer cell growth by decreasing mitochondrial membrane potential. This effect may be caused by the inhibition of mitochondrial ATP production or the disruption of ion transport across the mitochondrial membrane.

Formula: C₁₄H₉Cl₂NO

Purity: Min. 95%

Color and Shape: Slightly Yellow Powder

Molecular weight: 278.13 g/mol

Ref: 3D-FD29293