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CAS 86-54-4

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Hydralazine

Description:
Hydralazine is a pharmaceutical compound primarily used as an antihypertensive agent to treat high blood pressure. It is classified as a vasodilator, which means it works by relaxing the blood vessels, thereby reducing the workload on the heart and lowering blood pressure. The chemical formula for hydralazine is C8H8N4, and it features a hydrazine functional group, which contributes to its mechanism of action. Hydralazine is typically administered orally or intravenously and is often used in combination with other antihypertensive medications. Its pharmacokinetics include rapid absorption and metabolism in the liver, with a variable half-life among individuals. Common side effects may include headache, palpitations, and gastrointestinal disturbances. Due to its potential to cause reflex tachycardia and fluid retention, it is often prescribed alongside diuretics or beta-blockers. Hydralazine's use has been associated with the development of drug-induced lupus erythematosus in some patients, necessitating careful monitoring during treatment. Overall, hydralazine remains an important option in the management of hypertension, particularly in specific patient populations.
Formula:C8H8N4
InChI:InChI=1/C8H8N4/c9-11-8-7-4-2-1-3-6(7)5-10-12-8/h1-5H,9H2,(H,11,12)
InChI key:InChIKey=RPTUSVTUFVMDQK-UHFFFAOYSA-N
SMILES:N(N)=C1C=2C(C=NN1)=CC=CC2
Synonyms:
  • 1-Hydrazinophthalazine
  • 1-Hydrazinylphthalazine
  • 1-Phthalazinylhydrazine
  • Apresolin
  • Apresoline
  • Apressin
  • Apressin (pharmaceutical)
  • Aprezolin
  • Ba 5968
  • C 5968
  • See more synonyms
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