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CAS 86060-82-4

:

N(alpha)-fmoc-N(epsilon)-Z-L-lysine

Description:
N(alpha)-Fmoc-N(epsilon)-Z-L-lysine, with the CAS number 86060-82-4, is a protected derivative of the amino acid lysine, commonly used in peptide synthesis. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino terminus, allowing for selective reactions at the carboxyl end or the side chain. The "Z" (benzyloxycarbonyl) group protects the epsilon amino group of lysine, providing stability during synthesis and facilitating the formation of peptide bonds. This compound is typically white to off-white in appearance and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its stability under standard laboratory conditions makes it suitable for various synthetic applications, particularly in solid-phase peptide synthesis. The presence of these protective groups allows for the sequential addition of amino acids while minimizing side reactions, making it a valuable intermediate in the production of peptides and proteins for research and therapeutic purposes.
Formula:C29H30N2O6
InChI:InChI=1/C29H30N2O6/c32-27(33)26(16-8-9-17-30-28(34)36-18-20-10-2-1-3-11-20)31-29(35)37-19-25-23-14-6-4-12-21(23)22-13-5-7-15-24(22)25/h1-7,10-15,25-26H,8-9,16-19H2,(H,30,34)(H,31,35)(H,32,33)/t26-/m0/s1
SMILES:c1ccc(cc1)COC(=NCCCC[C@@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12)O
Synonyms:
  • na-fmoc-N-epsilon-cbz-L-lysine
  • Fmoc-Lys(Z)-OH
  • Fmoc-L-Lys(Z)-OH
  • N~6~-[(benzyloxy)carbonyl]-N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine
  • Nepsilon-Fmoc-Nalpha-Cbz-L-Lysine
  • Fmoc-Lys(Cbz)-OH
  • Fmoc-Lys(Z)
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