CAS 86060-85-7

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycine 2,3,4,5,6-pentafluorophenyl ester

Description:

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycine 2,3,4,5,6-pentafluorophenyl ester, commonly referred to as Fmoc-Gly-Pfp, is a chemical compound used primarily in peptide synthesis as a protecting group for the amino acid glycine. This compound features a fluorenylmethoxycarbonyl (Fmoc) group, which is a widely utilized protective group in solid-phase peptide synthesis due to its stability under basic conditions and ease of removal under mild acidic conditions. The presence of the pentafluorophenyl ester moiety enhances the reactivity of the compound, making it suitable for coupling reactions. The fluorinated aromatic ring contributes to the compound's unique electronic properties and hydrophobicity, which can influence solubility and interaction with other molecules. Fmoc-Gly-Pfp is typically handled under inert conditions to prevent degradation and is soluble in organic solvents like dichloromethane and dimethylformamide. Its applications extend beyond peptide synthesis to include studies in drug development and materials science, where the manipulation of peptide sequences is crucial.

Formula: C₂₃H₁₄F₅NO₄

InChI: InChI=1S/C23H14F5NO4/c24-17-18(25)20(27)22(21(28)19(17)26)33-16(30)9-29-23(31)32-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15H,9-10H2,(H,29,31)

InChI key: InChIKey=LBSDTBJWUJIFBO-UHFFFAOYSA-N

SMILES: C(OC(NCC(OC1=C(F)C(F)=C(F)C(F)=C1F)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Synonyms:

• Fmoc-Gly-Opfp
• Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 2,3,4,5,6-pentafluorophenyl ester
• Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, pentafluorophenyl ester
• N-(Fluorenylmethoxycarbonyl)glycine pentafluorophenyl ester
• N-9-Fluorenylmethoxycarbonylglycine pentafluorophenyl ester
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycine 2,3,4,5,6-pentafluorophenyl ester

Fmoc-Gly-OPfp

CAS: 86060-85-7

Bachem ID: 4011859.

Formula: C₂₃H₁₄F₅NO₄

Purity: 96.9%

Color and Shape: White

Molecular weight: 463.36

Ref: 01-4011859

Fmoc-Gly-Opfp

CAS: 86060-85-7

Formula: C₂₃H₁₄F₅NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 463.3536

Ref: IN-DA003QND

Fmoc-Gly-OPfp

CAS: 86060-85-7

Molecular weight: 463.35

Ref: 7W-GM1186

Fmoc-Gly-OPfp

CAS: 86060-85-7

Fmoc-Gly-OPfp

Purity: 98%

Molecular weight: 463.35g/mol

Ref: 54-PC48005

Fmoc-Gly-OPfp

CAS: 86060-85-7

M06246 - Fmoc-Gly-OPfp

Formula: C₂₃H₁₄F₅NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 463.36

Ref: 10-M06246