Fmoc-S-benzyl-L-cysteine pentafluoro-phenyl ester is a chemical compound commonly used in peptide synthesis and bioconjugation. It features a protected form of the amino acid cysteine, where the thiol group is modified to enhance stability and reactivity during synthetic processes. The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a temporary protective group for the amino functionality, allowing for selective reactions without interfering with other functional groups. The benzyl group attached to the sulfur atom provides additional steric hindrance, which can influence the reactivity and solubility of the compound. The pentafluorophenyl ester moiety enhances the electrophilicity of the carboxylic acid, facilitating coupling reactions in peptide synthesis. This compound is typically utilized in solid-phase peptide synthesis, where its unique characteristics allow for efficient incorporation of cysteine residues into peptides. Overall, its structural features make it a valuable reagent in the field of organic and medicinal chemistry, particularly in the development of peptide-based therapeutics.

fmoc-S-benzyl-L-cysteine pentafluoro-phenyl ester

86060-95-9: Fmoc-S-benzyl-L-cysteine pentafluoro-phenyl ester is a chemical compound commonly used in peptide synthesis and bioconjugation. It features a protected form of the amino acid cysteine, where the thiol group is modified to enhance stability and reactivity during synthetic processes. The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a temporary protective group for the amino functionality, allowing for selective reactions without interfering with other functional groups. The benzyl group attached to the sulfur atom provides additional steric hindrance, which can influence the reactivity and solubility of the compound. The pentafluorophenyl ester moiety enhances the electrophilicity of the carboxylic acid, facilitating coupling reactions in peptide synthesis. This compound is typically utilized in solid-phase peptide synthesis, where its unique characteristics allow for efficient incorporation of cysteine residues into peptides. Overall, its structural features make it a valuable reagent in the field of organic and medicinal chemistry, particularly in the development of peptide-based therapeutics.

CAS 86060-95-9

fmoc-S-benzyl-L-cysteine pentafluoro-phenyl ester

(R)-Perfluorophenyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(benzylthio)propanoate

Ref: IN-DA003QMZ

Fmoc-Cys(Bzl)-OPfp

Ref: 7W-GM5520