CAS 86060-99-3

fmoc-L-asparagine pentafluorophenyl ester

Description:

Fmoc-L-asparagine pentafluorophenyl ester is a chemical compound commonly used in peptide synthesis and biochemistry. It features the Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which is widely utilized to protect amino groups during the synthesis of peptides. The pentafluorophenyl ester moiety enhances the reactivity of the carboxylic acid group, facilitating the formation of peptide bonds. This compound is characterized by its stability under basic conditions and its ability to be deprotected under mild acidic conditions, allowing for selective removal of the Fmoc group without affecting other functional groups. The presence of the pentafluorophenyl group contributes to its lipophilicity and can influence the solubility and reactivity of the compound in various solvents. Fmoc-L-asparagine pentafluorophenyl ester is typically handled with care due to its potential reactivity and should be stored in a cool, dry place, away from light. Its applications extend to the synthesis of peptides for research in drug development, protein engineering, and other areas of biochemistry.

Formula: C₂₅H₁₇F₅N₂O₅

InChI: InChI=1/C25H17F5N2O5/c26-18-19(27)21(29)23(22(30)20(18)28)37-24(34)16(9-17(31)33)32-25(35)36-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16H,9-10H2,(H2,31,33)(H,32,35)/t16-/m0/s1

SMILES: c1ccc2c(c1)c1ccccc1C2COC(=N[C@@H](CC(=N)O)C(=O)Oc1c(c(c(c(c1F)F)F)F)F)O

Synonyms:

• Fmoc-Asn-Opfp

Fmoc-Asn-OPfp

CAS: 86060-99-3

Bachem ID: 4011838.

Formula: C₂₅H₁₇F₅N₂O₅

Purity: > 75%

Color and Shape: White Powder

Molecular weight: 520.41

Ref: 01-4011838

Fmoc-Asn-OPfp

CAS: 86060-99-3

Formula: C₂₅H₁₇F₅N₂O₅

Molecular weight: 520.4049

Ref: IN-DA004LPQ

Fmoc-Asn-OPfp

CAS: 86060-99-3

Molecular weight: 520.40

Ref: 7W-GM9985

Fmoc-Asn-OPfp

CAS: 86060-99-3

Fmoc-Asn-OPfp is an optical probe for the detection of epidermal growth factor (EGF). It has a hydroxyl group attached to a fatty acid with an amino group. The safety profile of Fmoc-Asn-OPfp has been shown in animal tests and it is not toxic to humans. This compound is also a long-term inhibitor of the enzyme that produces EGF, which can be used for the treatment of congenital heart diseases. Fmoc-Asn-OPfp is water soluble, which makes it convenient for use with optical systems such as microscopes. Fmoc-Asn-OPfp may be useful in the diagnosis and treatment of various other conditions, including human immunodeficiency virus (HIV) infection, cancer, and chronic kidney disease.

Formula: C₂₅H₁₇N₂O₅F₅

Purity: Min. 95%

Molecular weight: 520.4 g/mol

Ref: 3D-FF41624