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CAS 86093-76-7

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2-(Trifluoromethyl)thiophene

Description:
2-(Trifluoromethyl)thiophene is an organofluorine compound characterized by the presence of a thiophene ring, which is a five-membered aromatic heterocycle containing sulfur. The trifluoromethyl group (-CF3) is attached to the second carbon of the thiophene ring, significantly influencing its chemical properties. This compound is typically a colorless to pale yellow liquid with a distinctive odor. It exhibits high thermal stability and is relatively non-polar due to the presence of the electronegative fluorine atoms, which can enhance its reactivity in various chemical reactions, such as electrophilic substitutions. The trifluoromethyl group also imparts unique electronic properties, making it useful in the synthesis of pharmaceuticals and agrochemicals. Additionally, 2-(Trifluoromethyl)thiophene can participate in various reactions, including nucleophilic substitutions and cross-coupling reactions, making it a valuable intermediate in organic synthesis. Its applications extend to materials science, where it may be used in the development of functionalized polymers and other advanced materials.
Formula:C5H3F3S
InChI:InChI=1/C5H3F3S/c6-5(7,8)4-2-1-3-9-4/h1-3H
SMILES:c1cc(C(F)(F)F)sc1
Synonyms:
  • Thiophene, 2-(Trifluoromethyl)-
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