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CAS 86093-77-8

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3-(Trifluoromethyl)thiophene

Description:
3-(Trifluoromethyl)thiophene is a heterocyclic organic compound characterized by the presence of a thiophene ring substituted with a trifluoromethyl group at the 3-position. The molecular structure consists of a five-membered aromatic ring containing sulfur, which contributes to its unique electronic properties. The trifluoromethyl group (-CF3) is known for its strong electron-withdrawing effects, which can significantly influence the reactivity and stability of the compound. This substitution can enhance the compound's lipophilicity and alter its interaction with biological systems, making it of interest in various fields, including pharmaceuticals and agrochemicals. 3-(Trifluoromethyl)thiophene is typically a colorless to pale yellow liquid or solid, depending on its purity and specific conditions. It is soluble in organic solvents, and its chemical behavior can be studied through various reactions, including electrophilic substitutions and nucleophilic attacks. Overall, this compound serves as a valuable building block in synthetic organic chemistry, particularly in the development of functional materials and biologically active molecules.
Formula:C5H3F3S
InChI:InChI=1S/C5H3F3S/c6-5(7,8)4-1-2-9-3-4/h1-3H
InChI key:InChIKey=CORHGUPIEQAJDV-UHFFFAOYSA-N
SMILES:C(F)(F)(F)C=1C=CSC1
Synonyms:
  • 3-Trifluoromethylthiophene
  • Thiophene, 3-(trifluoromethyl)-
  • 3-(Trifluoromethyl)thiophene
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