
CAS 861020-53-3
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Found 2 products.
1-Benzyl-4-methylpiperazine dihydrochloride
CAS:Controlled Product1-Benzyl-4-methylpiperazine dihydrochloride (1BMP) is a structural analog of imatinib, which is an allosteric inhibitor of the enzyme b-raf. 1BMP binds to the ATP binding site on b-raf and prevents it from activating its target protein, the kinase enzyme that plays a key role in cell division. Imatinib has been shown to be effective in treating chronic myeloid leukemia and other cancers with mutations in the b-raf gene. Sorafenib, another allosteric inhibitor of b-raf, was also found to be effective against chronic myeloid leukemia, as well as pancreatic cancer and hepatocellular carcinoma.Formula:C12H20Cl2N2Purity:Min. 95%Molecular weight:263.2 g/mol

