CAS 86111-26-4

Zindoxifene

Description:

Zindoxifene is a synthetic compound classified as a selective estrogen receptor modulator (SERM). It is primarily investigated for its potential use in the treatment of hormone-dependent conditions, particularly breast cancer. Zindoxifene exhibits both estrogenic and anti-estrogenic properties, depending on the target tissue, which allows it to modulate estrogen receptor activity effectively. This dual action can help inhibit the proliferation of estrogen-sensitive tumors while potentially preserving beneficial estrogenic effects in other tissues, such as bone. The compound has been studied for its pharmacokinetic profile, which includes absorption, distribution, metabolism, and excretion characteristics that influence its therapeutic efficacy and safety. Additionally, Zindoxifene's chemical structure contributes to its ability to interact selectively with estrogen receptors, making it a subject of interest in ongoing research for cancer therapies and other estrogen-related disorders. As with any pharmaceutical agent, understanding its mechanism of action, side effects, and interactions with other medications is crucial for its clinical application.

Formula: C₂₁H₂₁NO₄

InChI: InChI=1S/C21H21NO4/c1-5-22-20-11-10-18(26-15(4)24)12-19(20)13(2)21(22)16-6-8-17(9-7-16)25-14(3)23/h6-12H,5H2,1-4H3

InChI key: InChIKey=KSZGVNZSUJHOJA-UHFFFAOYSA-N

SMILES: C(C)N1C(=C(C)C=2C1=CC=C(OC(C)=O)C2)C3=CC=C(OC(C)=O)C=C3

Synonyms:

• D 16726
• 1-Ethyl-2-(p-hydroxyphenyl)-3-methylindol-5-ol diacetate (ester)
• 1H-Indol-5-ol, 2-[4-(acetyloxy)phenyl]-1-ethyl-3-methyl-, acetate (ester)
• 5-Acetoxy-2-(4-acetoxyphenyl)-1-ethyl-3-methylindole
• UNII-1IRS95M8DN
• Zindoxifenum [Latin]
• 2-(4-(Acetyloxy)phenyl)-1-ethyl-3-methyl-1H-indol-5-ol acetate (ester)
• 1H-Indol-5-ol, 2-[4-(acetyloxy)phenyl]-1-ethyl-3-methyl-, 5-acetate
• NSC 341952
• Zindoxifenum
• BRN 4885631
• Zindoxifene
• Zindoxifene [INN]
• Zindoxifeno
• Zindoxifeno [Spanish]
• NSC-341952
• 1H-Indol-5-ol, 2-(4-(acetyloxy)phenyl)-1-ethyl-3-methyl-, acetate (ester)
• 4-[5-(acetyloxy)-1-ethyl-3-methyl-1H-indol-2-yl]phenyl acetate

Zindoxifene

CAS: 86111-26-4

Zindoxifene

Purity: ≥98%

Molecular weight: 351.4g/mol

Ref: 54-BUP03217

Zindoxifene

CAS: 86111-26-4

Zindoxifene (D 16726) is an anti-estrogenic compound with antitumor activity that can be used in studies of breast and prostate cancer.

Formula: C₂₁H₂₁NO₄

Purity: 98.99%

Color and Shape: Solid

Molecular weight: 351.4

Ref: TM-T23647