CAS 861151-12-4

N-Piperidinyl-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4,5-dihydro-1H-pyrazole-3-carboxamide

Description:

N-Piperidinyl-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4,5-dihydro-1H-pyrazole-3-carboxamide, with the CAS number 861151-12-4, is a synthetic organic compound characterized by its complex structure, which includes a pyrazole core substituted with various aromatic and heterocyclic groups. This compound typically exhibits properties such as moderate solubility in organic solvents and potential bioactivity, making it of interest in medicinal chemistry. The presence of multiple chlorine atoms in its structure suggests that it may possess unique electronic properties, potentially influencing its reactivity and interaction with biological targets. The piperidine moiety contributes to its pharmacological profile, possibly enhancing its ability to cross biological membranes. As a carboxamide, it may also engage in hydrogen bonding, which can affect its stability and solubility. Overall, this compound's characteristics make it a candidate for further investigation in drug development, particularly in areas related to its therapeutic potential and mechanism of action.

Formula: C₂₁H₂₁Cl₃N₄O

InChI: InChI=1S/C21H21Cl3N4O/c22-15-6-4-14(5-7-15)20-13-18(21(29)26-27-10-2-1-3-11-27)25-28(20)19-9-8-16(23)12-17(19)24/h4-9,12,20H,1-3,10-11,13H2,(H,26,29)

InChI key: InChIKey=WMMMJGKFKKBRQR-UHFFFAOYSA-N

SMILES: ClC1=C(N2C(CC(C(NN3CCCCC3)=O)=N2)C4=CC=C(Cl)C=C4)C=CC(Cl)=C1

Synonyms:

• 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4,5-dihydro-N-1-piperidinyl-1H-pyrazole-3-carboxamide
• N-Piperidinyl-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4,5-dihydro-1H-pyrazole-3-carboxamide
• Rosonabant
• N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4,5-dihydro-1H-pyrazole-3-carboxamide
• 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4,5-dihydro-N-1-piperidinyl-

Rosonabant

CAS: 861151-12-4

Rosonabant (E-6776）is a CB1 receptor antagonist/reverse agonist that is studying as an appetite suppressant for the treatment of obesity.

Formula: C₂₁H₂₁Cl₃N₄O

Color and Shape: Solid

Molecular weight: 451.78

Ref: TM-T34392