CAS 86163-30-6

Thymidine, a-oxo-, 3',5'-diacetate

Description:

Thymidine, a-oxo-, 3',5'-diacetate, also known by its CAS number 86163-30-6, is a synthetic derivative of thymidine, a nucleoside that plays a crucial role in DNA synthesis. This compound features acetyl groups at the 3' and 5' hydroxyl positions, which enhances its stability and solubility compared to unmodified thymidine. The presence of the a-oxo group indicates a ketone functionality, which can influence its reactivity and biological interactions. Thymidine derivatives are often utilized in biochemical research, particularly in studies involving DNA replication and repair, as well as in the development of antiviral and anticancer agents. The acetylation of thymidine can also affect its ability to be incorporated into nucleic acids, making it a valuable tool in molecular biology. Overall, thymidine, a-oxo-, 3',5'-diacetate is characterized by its structural modifications that enhance its chemical properties and potential applications in various fields of research.

Formula: C₁₄H₁₆N₂O₈

3',5'-Di-O-acetyl-2'-deoxy-5-formyluridine

CAS: 86163-30-6

3',5'-Di-O-acetyl-2'-deoxy-5-formyluridine is a novel antiviral agent that is active against viruses of the herpes family. It also has anticancer properties, and may be used to treat leukemia. 3',5'-Di-O-acetyl-2'-deoxy-5-formyluridine inhibits viral DNA synthesis by binding to the ribonucleoside triphosphate at the 5' position of the growing chain, preventing further elongation. This compound also inhibits bacterial growth by inhibiting DNA synthesis and protein synthesis. 3',5'-Di-O-acetyl-2'-deoxy-5-formyluridine can be activated by diphosphorylation to form a nucleoside phosphoramidite that can be used for chemical syntheses of oligonucleotides and other nucleic acids.
3',5'-Di-O-acetyl-2'-deoxy

Formula: C₁₄H₁₆N₂O₈

Purity: Min. 95 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 340.29 g/mol

Ref: 3D-ND180251