CAS 86168-78-7

sermorelin

Description:

Sermorelin, with the CAS number 86168-78-7, is a synthetic peptide that functions as a growth hormone-releasing hormone (GHRH) analog. It consists of 29 amino acids and is primarily used in clinical settings to stimulate the secretion of growth hormone from the pituitary gland. Sermorelin is characterized by its ability to enhance endogenous growth hormone production, making it a potential therapeutic option for conditions related to growth hormone deficiency. The peptide is typically administered via subcutaneous injection and has a relatively short half-life, necessitating multiple doses for sustained effects. Its mechanism of action involves binding to specific receptors on pituitary cells, leading to increased release of growth hormone. Sermorelin is often studied for its potential benefits in anti-aging therapies, muscle growth, and overall metabolic health. However, its use should be monitored by healthcare professionals due to possible side effects and the need for appropriate dosing. As with any peptide therapy, the regulatory status and clinical applications may vary by region.

Formula: C₁₄₉H₂₄₆N₄₄O₄₂S

InChI: InChI=1/C149H246N44O42S/c1-20-77(13)116(191-122(211)81(17)168-132(221)104(66-113(204)205)178-121(210)79(15)167-123(212)88(152)62-84-39-43-86(198)44-40-84)145(234)185-102(63-83-32-23-22-24-33-83)138(227)193-118(82(18)197)146(235)186-103(65-111(155)202)137(226)189-108(71-196)142(231)182-101(64-85-41-45-87(199)46-42-85)136(225)175-93(38-31-56-165-149(161)162)126(215)174-91(35-26-28-53-151)131(220)190-115(76(11)12)143(232)184-97(58-72(3)4)124(213)166-68-112(203)170-94(47-49-109(153)200)128(217)180-100(61-75(9)10)135(224)188-106(69-194)140(229)169-80(16)120(209)172-92(37-30-55-164-148(159)160)125(214)173-90(34-25-27-52-150)127(216)179-99(60-74(7)8)134(223)181-98(59-73(5)6)133(222)176-95(48-50-110(154)201)129(218)183-105(67-114(206)207)139(228)192-117(78(14)21-2)144(233)177-96(51-57-236-19)130(219)187-107(70-195)141(230)171-89(119(156)208)36-29-54-163-147(157)158/h22-24,32-33,39-46,72-82,88-108,115-118,194-199H,20-21,25-31,34-38,47-71,150-152H2,1-19H3,(H2,153,200)(H2,154,201)(H2,155,202)(H2,156,208)(H,166,213)(H,167,212)(H,168,221)(H,169,229)(H,170,203)(H,171,230)(H,172,209)(H,173,214)(H,174,215)(H,175,225)(H,176,222)(H,177,233)(H,178,210)(H,179,216)(H,180,217)(H,181,223)(H,182,231)(H,183,218)(H,184,232)(H,185,234)(H,186,235)(H,187,219)(H,188,224)(H,189,226)(H,190,220)(H,191,211)(H,192,228)(H,193,227)(H,204,205)(H,206,207)(H4,157,158,163)(H4,159,160,164)(H4,161,162,165)

Synonyms:

• GRF (1-29) amide (human)
• H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
• growth hormone releasing factor*fragment 1-29 ami

Growth Hormone Releasing Factor (GRF) (1-29) amide, human

CAS: 86168-78-7

Growth Hormone Releasing Factor (GRF) (1-29) amide, human

Formula: C₁₄₉H₂₄₆N₄₄O₄₂S

Molecular weight: 3357.9

Ref: 02-J61111

GRF (1-29) amide (human)

CAS: 86168-78-7

GRF (1-29) amide (sermorelin) is the shortest GRF fragment with full biological activity. CAS Number (sermorelin acetate): 114466-38-5.

Formula: C₁₄₉H₂₄₆N₄₄O₄₂S

Purity: 97.6%

Color and Shape: White Powder

Molecular weight: 3357.93

Ref: 01-4030689

Sermorelin acetate

CAS: 86168-78-7

Formula: C₁₅₁H₂₅₀N₄₄O₄₄S

Purity: (HPLC) ≥ 99.0%

Color and Shape: White to off-white solid

Molecular weight: 3417.99

Ref: 7W-GX6869

GRF (1-29) amide (human) acetate salt

CAS: 86168-78-7

Growth hormone-releasing factor (GRF) is a peptide fragment of amino acids 1–2 from GHRH (growth hormone-releasing hormone). This 1-29 region is the shortest fully functional fragment of GHRH. GRF is also known as sermorelin. Sermorelin binds to the growth hormone-releasing hormone receptor (GHRH-R), and acts as a surrogate for GHRH, causing growth hormone secretion.human: H-YADAIFTNSYRKVLGQLSARKLLQDIMSR-NH2rat:        H-HADAIFTSSYRR I LGQLYARKLLHEIMNR-NH2

Formula: C₁₄₉H₂₄₆N₄₄O₄₂S

Purity: Min. 95%

Molecular weight: 3,357.88 g/mol

Ref: 3D-FG109068