CAS 861998-00-7

Anamorelin HCl

Description:

Anamorelin HCl is a synthetic compound classified as a selective ghrelin receptor agonist, primarily developed for its potential use in treating cachexia, a condition characterized by severe weight loss and muscle wasting often associated with chronic illnesses. The substance acts by mimicking the action of ghrelin, a hormone that stimulates appetite and promotes weight gain by enhancing food intake and increasing energy expenditure. Anamorelin HCl is typically administered in its hydrochloride salt form, which enhances its solubility and stability. The compound has been studied for its effects on body weight, lean body mass, and overall quality of life in patients with cancer-related cachexia. Its mechanism of action involves the activation of growth hormone secretagogue receptors, leading to increased growth hormone release and subsequent metabolic effects. While promising in clinical trials, the safety profile and long-term effects of Anamorelin HCl continue to be evaluated to ensure its efficacy and minimize potential side effects in therapeutic applications.

AnaMorelin hydrochloride

CAS: 861998-00-7

AnaMorelin hydrochloride (RC-1291 hydrochloride) is a novel ghrelin receptor agonist(EC50 : 0.74 nM, in the FLIPR assay).

Formula: C₃₁H₄₃ClN₆O₃

Purity: 99.18% - ≥98%

Color and Shape: Solid

Molecular weight: 583.16

Ref: TM-T7225

Anamorelin Hydrochloride

Controlled Product

CAS: 861998-00-7

Applications Anamorelin Hydrochloride can be used in biological study and therapeutic use for treatment of cancer-anorexia-cachexia in non-small-cell lung carcinoma patients.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhang, H., et al.: Expert Opin Pharmaco,

Formula: C₃₁H₄₂N₆O₃·HCl

Color and Shape: Neat

Molecular weight: 546.70 + 36.46

Ref: TR-A637225

Anamorelin hydrochloride

CAS: 861998-00-7

Anamorelin hydrochloride is a peptide hormone that has been investigated for the treatment of cancer and metabolic disorders. It has also been used in clinical trials for cachexia, a condition where weight loss is caused by chronic illness or injury. The drug binds to ghrelin receptors in the gastrointestinal tract and stimulates appetite, leading to improved weight gain and reduced energy expenditure. Anamorelin hydrochloride may be used as an adjuvant therapy for patients with bowel diseases such as Crohn's disease or ulcerative colitis. It has also been shown to have immunomodulatory effects in vitro and in vivo assays.

Formula: C₃₁H₄₃ClN₆O₃

Purity: Min. 95%

Molecular weight: 583.16 g/mol

Ref: 3D-LJB99800