CAS 862156-92-1

Sitagliptin Monohydrochloride Monohydrate

CAS: 862156-92-1

Applications Sitagliptin Monohydrochloride Monohydrate has therapeutic applications and is used in pharmaceutical compositions in the form of immediate release tablets.
References Arroyo Hidalgo, S., & Pladevall Roses, M.: PCT Int. Appl. (2015), WO 2015114152 A1

Formula: C₁₆H₁₅F₆N₅O·HCl·H₂O

Color and Shape: Neat

Molecular weight: 407.31 + 36.46 + 18.02

Ref: TR-S491050

Sitagliptin Hydrochloride Hydrate

CAS: 862156-92-1

Formula: C₁₆H₁₅F₆N₅OHClH₂O

Molecular weight: 407.32 : 36.5 : 18.0

Ref: ST-EA-CP-S3032

Sitagliptin monohydrochloride monohydrate

CAS: 862156-92-1

Sitagliptin monohydrochloride monohydrate is an inhibitor of dipeptidyl peptidase-4 (DPP-4), which is responsible for the degradation of incretin hormones. It is used in the treatment of type 2 diabetes mellitus, as it increases insulin secretion and reduces blood glucose levels. Recent studies have shown that Sitagliptin has anticancer properties, as it induces apoptosis in cancer cells. It also inhibits protein kinases, which are involved in tumor growth and metastasis. Capsaicin, a compound found in chili peppers, has been shown to enhance the anticancer activity of Sitagliptin in Chinese hamster ovary cells. The drug is excreted primarily through urine and has a low potential for drug interactions with other kinase inhibitors. Overall, Sitagliptin monohydrochloride monohydrate shows great promise as both a diabetes medication and an anticancer agent.

Formula: C₁₆H₁₈ClF₆N₅O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 461.79 g/mol

Ref: 3D-MJB15692