Diclofenac 13C6 sodium hydrate is a labeled form of the nonsteroidal anti-inflammatory drug (NSAID) diclofenac, which is commonly used to relieve pain and reduce inflammation. The "13C6" designation indicates that the compound contains six carbon atoms that are isotopically enriched with carbon-13, a stable isotope of carbon. This labeling is often utilized in pharmacokinetic studies to trace the drug's metabolism and distribution in biological systems. The sodium salt form enhances the solubility of diclofenac in aqueous solutions, making it more bioavailable for therapeutic use. As a hydrate, it contains water molecules in its crystalline structure, which can influence its stability and solubility. Diclofenac works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), leading to decreased synthesis of prostaglandins, which are mediators of inflammation and pain. The compound is typically administered in various formulations, including tablets and injections, and is subject to regulatory oversight due to its pharmacological effects and potential side effects.

Diclofenac 13C6 sodium hydrate

862243-45-6: Diclofenac 13C6 sodium hydrate is a labeled form of the nonsteroidal anti-inflammatory drug (NSAID) diclofenac, which is commonly used to relieve pain and reduce inflammation. The "13C6" designation indicates that the compound contains six carbon atoms that are isotopically enriched with carbon-13, a stable isotope of carbon. This labeling is often utilized in pharmacokinetic studies to trace the drug's metabolism and distribution in biological systems. The sodium salt form enhances the solubility of diclofenac in aqueous solutions, making it more bioavailable for therapeutic use. As a hydrate, it contains water molecules in its crystalline structure, which can influence its stability and solubility. Diclofenac works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), leading to decreased synthesis of prostaglandins, which are mediators of inflammation and pain. The compound is typically administered in various formulations, including tablets and injections, and is subject to regulatory oversight due to its pharmacological effects and potential side effects.

<p>Applications 6-Cyano Diclazuril-13C3,15N2 is an intermediate for the synthesis of Diclazuril-13C3,15N2 (D436202), which is the labelled analogue of Diclazuril (D436200). Diclazuril is a nucleotide analogue with broad-spectrum anticoccidial activity and a coccidiostat.<br>References Maes, L., et al.: J. Parasitol., 74, 931 (1988)<br></p>

CAS 862243-45-6

Diclofenac 13C6 sodium hydrate

6-Cyano Diclazuril-13C3,15N2

Ref: TR-C894252