CAS 862269-93-0

N-{4-[(6-{4-[(1R)-1-(4-fluorophenyl)ethyl]piperazin-1-yl}pyrimidin-4-yl)oxy]-1,3-benzothiazol-2-yl}acetamide

Description:

N-{4-[(6-{4-[(1R)-1-(4-fluorophenyl)ethyl]piperazin-1-yl}pyrimidin-4-yl)oxy]-1,3-benzothiazol-2-yl}acetamide, with CAS number 862269-93-0, is a synthetic organic compound characterized by its complex molecular structure, which includes multiple functional groups such as an acetamide, a benzothiazole, and a piperazine moiety. This compound is typically classified as a small molecule and may exhibit pharmacological properties, potentially acting as a therapeutic agent in various biological systems. Its structure suggests it may interact with specific biological targets, possibly influencing pathways related to neurological or oncological conditions. The presence of a fluorophenyl group may enhance its lipophilicity and bioavailability. Additionally, the compound's solubility, stability, and reactivity can be influenced by its functional groups and overall molecular architecture. As with many synthetic compounds, its safety profile, including toxicity and side effects, would need to be evaluated through rigorous testing in preclinical and clinical studies.

Formula: C₂₅H₂₅FN₆O₂S

Synonyms:

• AMG-628, (R)-
• Acetamide, N-[4-[[6-[4-[(1R)-1-(4-fluorophenyl)ethyl]-1-piperazinyl]-4-pyrimidinyl]oxy]-2-benzothiazolyl]-
• N-{4-[(6-{4-[(1R)-1-(4-fluorophenyl)ethyl]piperazin-1-yl}pyrimidin-4-yl)oxy]-1,3-benzothiazol-2-yl}acetamide

AMG-628, (R)-

CAS: 862269-93-0

R-isomer AMG-628 is a selective ATP-competitive inhibitor of Raf kinases, blocking growth and inducing apoptosis in B-RafV600E mutant cells.

Formula: C₂₅H₂₅FN₆O₂S

Color and Shape: Solid

Molecular weight: 492.57

Ref: TM-T71736