CAS 862309-06-6

4(3H)-Quinazolinone,2-methyl-3-[4-[3-(1-pyrrolidinyl)propoxy]phenyl]-5-(trifluoromethyl)-

Description:

4(3H)-Quinazolinone, 2-methyl-3-[4-[3-(1-pyrrolidinyl)propoxy]phenyl]-5-(trifluoromethyl)- is a synthetic organic compound characterized by its quinazolinone core structure, which is a bicyclic compound containing a fused benzene and pyrimidine ring. This particular derivative features a methyl group at the 2-position, a trifluoromethyl group at the 5-position, and a phenyl ring substituted with a propoxy group linked to a pyrrolidine moiety. The presence of the trifluoromethyl group often enhances lipophilicity and biological activity, making such compounds of interest in medicinal chemistry. The pyrrolidine ring contributes to the compound's potential pharmacological properties, possibly influencing receptor interactions or enzyme inhibition. The compound's molecular structure suggests it may exhibit various biological activities, including potential use as a therapeutic agent. Its CAS number, 862309-06-6, allows for precise identification in chemical databases, facilitating research and development in pharmaceutical applications.

Formula: C₂₃H₂₄F₃N₃O₂

MK-0249

CAS: 862309-06-6

MK-0249

Purity: ≥98%

Molecular weight: 431.45g/mol

Ref: 54-BUP08587

MK-0249

CAS: 862309-06-6

MK-0249 is a potent inhibitor of hyaluronan-mediated tumor cell proliferation and migration. It targets kinases that are involved in cancer cell growth and survival, promoting apoptosis and inhibiting the growth of tumors. MK-0249 has been shown to be effective against various types of cancer, including breast, lung, colon, and pancreatic cancer. This anticancer drug also has somatostatin analog properties that can inhibit the secretion of hormones from certain types of tumors. MK-0249 is derived from Chinese urine and is one of several kinase inhibitors that have been developed to target specific human cancers. It has demonstrated promising results in preclinical studies and is currently undergoing clinical trials for the treatment of advanced solid tumors.

Formula: C₂₃H₂₄F₃N₃O₂

Purity: Min. 95%

Molecular weight: 431.4 g/mol

Ref: 3D-MJB30906

MK-0249

CAS: 862309-06-6

MK-0249 is a potent antagonist of histamine H3 receptor (human H3, Ki : 1.7 nM).

Formula: C₂₃H₂₄F₃N₃O₂

Purity: 99.90%

Color and Shape: Solid

Molecular weight: 431.45

Ref: TM-T12054