CAS 862811-76-5

NCGC00135472

CAS: 862811-76-5

NCGC00135472

Purity: ≥98%

Molecular weight: 364.35g/mol

Ref: 54-BUP07275

3,4-Difluoro-N-(3-{3-methylimidazo[1,2-a]pyrimidin-2-yl}phenyl)benzamide

CAS: 862811-76-5

3,4-Difluoro-N-(3-{3-methylimidazo[1,2-a]pyrimidin-2-yl}phenyl)benzamide is a potent and selective inhibitor of the voltage gated potassium channel Kv1.4 with IC50 of 0.5 nM. It has been used as a research tool for its ability to inhibit the activation of ion channels. 3,4-Difluoro-N-(3-{3-methylimidazo[1,2-a]pyrimidin-2-yl}phenyl)benzamide is also an inhibitor of protein interactions and receptor ligand binding. This compound binds to the receptor site of the voltage gated potassium channel and prevents it from opening, which results in reduced excitability of neurons.

Formula: C₂₀H₁₄F₂N₄O

Purity: Min. 95%

Molecular weight: 364.3 g/mol

Ref: 3D-MJB81176

NCGC00135472

CAS: 862811-76-5

NCGC00135472: DRV1 agonist with pro-catabolic effects, activates DRV1/GPR32, EC50: 0.37 uM (beta-blocker), 0.05 uM (cAMP), enhances phagocytosis.

Formula: C₂₀H₁₄F₂N₄O

Purity: 99.41% - 99.48%

Color and Shape: Solid

Molecular weight: 364.35

Ref: TM-T33613