10-Methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one is a complex heterocyclic compound characterized by its fused indole and naphthyridine structures. This compound features a methoxy group (-OCH3) at the 10-position, which can influence its solubility and reactivity. The presence of the indole moiety contributes to its potential biological activity, as indole derivatives are known for various pharmacological properties, including antimicrobial and anticancer effects. The naphthyridine component adds to the compound's aromatic character, which may enhance its stability and interaction with biological targets. The molecular structure suggests that it may participate in hydrogen bonding and π-π stacking interactions, which are important in drug design and molecular recognition. Additionally, the compound's unique arrangement of nitrogen and carbon atoms may confer specific electronic properties, making it a subject of interest in medicinal chemistry and material science. Overall, 10-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one represents a fascinating area of study due to its structural complexity and potential applications.

10-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one

86293-40-5: 10-Methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one is a complex heterocyclic compound characterized by its fused indole and naphthyridine structures. This compound features a methoxy group (-OCH3) at the 10-position, which can influence its solubility and reactivity. The presence of the indole moiety contributes to its potential biological activity, as indole derivatives are known for various pharmacological properties, including antimicrobial and anticancer effects. The naphthyridine component adds to the compound's aromatic character, which may enhance its stability and interaction with biological targets. The molecular structure suggests that it may participate in hydrogen bonding and π-π stacking interactions, which are important in drug design and molecular recognition. Additionally, the compound's unique arrangement of nitrogen and carbon atoms may confer specific electronic properties, making it a subject of interest in medicinal chemistry and material science. Overall, 10-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one represents a fascinating area of study due to its structural complexity and potential applications.

10-Methoxy-canthin-6-one (Mtx-C) acts as a DNA damage inducer that embeds into DNA, promoting cell cycle arrest at the G2/M phase. This process triggers myeloid differentiation in acute myeloid leukemia cells (AML) and leukemia stem cells (LSC). Differentiation in AML and LSC cells is characterized by increased expression of myeloperoxidase, CD15, CD11b, and CD14, along with the activation of p38 MAPK. 10-Methoxy-canthin-6-one is utilized in the study of leukemia.

CAS 86293-40-5

10-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one

10-Methoxy-canthin-6-one

Ref: TM-T200611