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CAS 86304-28-1

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Buciclovir

Description:
Buciclovir is an antiviral compound primarily studied for its potential use in treating viral infections, particularly those caused by herpes viruses. It belongs to the class of nucleoside analogs, which function by mimicking the building blocks of DNA or RNA, thereby interfering with viral replication. Buciclovir exhibits a structure that allows it to be selectively activated by viral enzymes, enhancing its efficacy against infected cells while minimizing effects on uninfected cells. The compound has shown promise in preclinical studies, demonstrating activity against various strains of herpes simplex virus and cytomegalovirus. Its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are critical for determining its therapeutic potential and safety profile. As with many antiviral agents, the development of resistance is a concern, necessitating ongoing research to optimize its use and explore combination therapies. Overall, Buciclovir represents a significant area of interest in antiviral drug development, particularly for patients with resistant viral infections.
Formula:C9H13N5O3
InChI:InChI=1S/C9H13N5O3/c10-9-12-7-6(8(17)13-9)11-4-14(7)2-1-5(16)3-15/h4-5,15-16H,1-3H2,(H3,10,12,13,17)/t5-/m1/s1
InChI key:InChIKey=QOVUZUCXPAZXDZ-RXMQYKEDSA-N
SMILES:C(C[C@H](CO)O)N1C2=C(N=C1)C(=O)N=C(N)N2
Synonyms:
  • 6H-Purin-6-one, 2-amino-9-(3,4-dihydroxybutyl)-1,9-dihydro-, (R)-
  • 2-Amino-9-[(3R)-3,4-dihydroxybutyl]-1,9-dihydro-6H-purin-6-one
  • Buciclovir
  • (R)-9-(3,4-Dihydroxybutyl)guanine
  • 6H-Purin-6-one, 2-amino-9-[(3R)-3,4-dihydroxybutyl]-1,9-dihydro-
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