CAS 863456-50-2

b-D-Glucopyranuronic acid,1-O-[[1,8-dioxo-8-(phenylamino)octyl]amino]-

Description:

β-D-Glucopyranuronic acid, 1-O-[[1,8-dioxo-8-(phenylamino)octyl]amino]- is a chemical compound that features a glucuronic acid moiety, which is a derivative of glucose and plays a significant role in various biological processes, including detoxification and metabolism. The presence of the 1-O-[[1,8-dioxo-8-(phenylamino)octyl]amino]- group indicates that this compound has been modified to include an aminoalkyl chain with a phenyl group, which may enhance its solubility or biological activity. The dioxo structure suggests potential reactivity, possibly allowing for interactions with biological targets or other chemical species. This compound may exhibit properties such as being a potential drug candidate or a biochemical probe due to its structural features. Its solubility, stability, and reactivity would depend on the specific conditions, including pH and solvent, making it important for applications in medicinal chemistry or biochemistry. Further studies would be necessary to elucidate its specific biological functions and potential therapeutic applications.

Formula: C₂₀H₂₈N₂O₉

Synonyms:

• 1-O-[[1,8-Dioxo-8-(phenylamino)octyl]amino]-b-D-glucopyranuronic Acid
• Suberoylanilide Hydroxamic Acid b-D-Glucuronide
• 1-O-[[1,8-Dioxo-8-(phenylamino)octyl]amino]--D-glucopyranuronic Acid
• Suberoylanilide Hydroxamic Acid -D-Glucuronide

Suberoylanilide hydroxamic acid b-D-glucuronide

CAS: 863456-50-2

Ref: 7W-GC7950

Suberoylanilide Hydroxamic Acid β-D-Glucuronide Sodium Salt

Controlled Product

CAS: 863456-50-2

Formula: C₂₀H₂₇N₂NaO₉

Color and Shape: Neat

Molecular weight: 462.43

Ref: TR-S688715

Suberoylanilide-d5 Hydroxamic Acid β-D-Glucuronide

Controlled Product

CAS: 863456-50-2

Applications The labelled metabolite (MI) of Suberoylanilide Hydroxamic Acid.
References Sun, W.S., et al.: J. Med. Chem., 46, 5619 (2003)

Formula: C₂₀H₂₃D₅N₂O₉

Color and Shape: Neat

Molecular weight: 445.48

Ref: TR-S688712

Suberoylanilide hydroxamic acid b-D-glucuronide

CAS: 863456-50-2

Suberoylanilide hydroxamic acid b-D-glucuronide (SAHA) is a histone deacetylase inhibitor that is used in the treatment of colorectal adenocarcinoma. It is orally administered and can cross the blood-brain barrier to inhibit HDACs in human liver cells. SAHA has been shown to be effective against a number of cancer cell lines, including colon, prostate, breast, lung, and leukemia cell lines. SAHA has also been shown to have clinical benefits in various cancers and has been found to be safe at doses up to 1g/day when given for 24 months. The most common side effects are thrombocytopenia and anorexia.

Formula: C₂₀H₂₈N₂O₉

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 440.44 g/mol

Ref: 3D-MS07390