CAS 86347-14-0
:Medetomidine
Description:
Medetomidine is a selective alpha-2 adrenergic agonist primarily used in veterinary medicine as a sedative and analgesic agent. It is characterized by its ability to induce sedation, muscle relaxation, and analgesia, making it particularly useful in procedures requiring anesthesia in animals. Medetomidine acts by binding to alpha-2 adrenergic receptors in the central nervous system, leading to decreased norepinephrine release and resulting in sedation and pain relief. The substance is typically administered via injection and has a rapid onset of action. Its pharmacokinetics include a relatively short half-life, necessitating careful monitoring and potential use of reversal agents, such as atipamezole, to counteract its effects when necessary. Medetomidine is also known for its cardiovascular effects, which can include bradycardia and hypotension, requiring caution in animals with pre-existing health conditions. Overall, medetomidine is a valuable tool in veterinary anesthesia, providing effective sedation and analgesia while requiring careful management to mitigate potential side effects.
Formula:C13H16N2
InChI:InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)
InChI key:InChIKey=CUHVIMMYOGQXCV-UHFFFAOYSA-N
SMILES:C(C)(C1=C(C)C(C)=CC=C1)C2=CN=CN2
Synonyms:- ( -)-4-(alpha,2,3-Trimethylbenzyl)imidazole
- (RS)-4-(alpha,2,3-Trimethylbenzyl)imidazol
- 1H-Imidazole, 4-(1-(2,3-dimethylphenyl)ethyl)-
- 1H-Imidazole, 5-[1-(2,3-dimethylphenyl)ethyl]-
- 5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
- Medetomidina
- Medetomidina [Spanish]
- Medetomidinum
- Medetomidinum [Latin]
- Selektope
- Slectope
- Unii-Mr15E85Mqm
- dl-Medetomidine
- See more synonyms
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Found 8 products.
Medetomidine-d5 (d5-Major)
CAS:Controlled Product<p>Applications Medetomidine-d5 (d5-Major) is an intermediate in the synthesis of Dexmedetomidine-d4 L-Tartrate (d4-Major) (D299006). Dexmedetomidine-d4 L-Tartrate is the labeled salt analogue of Dexmedetomidine (D299000), an α2-Adrenergic agonist; (+)-isomer of Medetomidine; sedative; analgesic.<br>References Rajala, R., et al.: Eur. J. Pharm. Sci., 1, 219 (1994); Jalonen, J., et al.: Anesthesiology, 86, 331 (1997); Talke, P., et al.: Anesth. Analg., 85, 1136 (1997); Bhana, N., et al.: Drugs, 59, 263 (2000)<br></p>Formula:C13D5H11N2Color and Shape:NeatMolecular weight:205.31Medetomidine
CAS:<p>Medetomidine (MPV785 free base) is a selective α2-adrenoceptor agonist, with sedative and analgesic and vasoconstrictive hypoxic , in small animal anesthesia.</p>Formula:C13H16N2Purity:99.88%Color and Shape:SolidMolecular weight:200.28Medetomidine
CAS:Controlled Product<p>Medetomidine is an experimental drug that belongs to the group of solubility data. It is a highly selective α-2 adrenergic agonist that has been used in experimental studies to study the central and peripheral effects of the drug. Medetomidine has been shown to induce natriuretic peptide levels and intracellular calcium levels in anesthetized animals. This drug also affects locomotor activity and enzyme activities, which may be due to its ability to increase corticosterone levels. The dexmedetomidine-medetomidine combination was found to produce sedation with minimal cardiovascular effects. The model system used for this study consisted of sedated rats receiving a single intravenous injection of medetomidine or dexmedetomidine alone or in combination with medetomidine. Medetomidine is soluble in water and methanol, but insoluble in ethanol and ether.</p>Formula:C13H16N2Purity:Min. 95%Molecular weight:200.28 g/mol
