CAS 86357-09-7

Iso Ganciclovir

Description:

Iso Ganciclovir, with the CAS number 86357-09-7, is a synthetic antiviral compound that is structurally related to ganciclovir, which is primarily used in the treatment of cytomegalovirus (CMV) infections. Iso Ganciclovir exhibits similar pharmacological properties, functioning as a nucleoside analog that interferes with viral DNA synthesis. Its mechanism of action involves the inhibition of viral DNA polymerase, thereby preventing the replication of viral genetic material. The compound is characterized by its ability to selectively target infected cells, which enhances its therapeutic efficacy while minimizing toxicity to uninfected cells. Iso Ganciclovir is typically administered in a clinical setting, and its effectiveness is often evaluated in the context of viral resistance and patient response. As with many antiviral agents, potential side effects may include hematological toxicity and other systemic reactions. Research continues to explore its full potential and applications in virology, particularly in the context of resistant strains of viruses.

Formula: C₉H₁₃N₅O₄

Synonyms:

• Gancyclovir Impurity 9
• Ganciclovir impurities815
• Ganciclovir Related Compound A (15 mg) ((RS)-2-Amino-9-(2,3-dihydroxy-propoxymethyl)-1,9-dihydro-purin-6-one)
• 3-[(2-Amino-6-hydroxy-9H-purin-9-yl)methoxy]-1,2-propanediol
• 6H-Purin-6-one, 2-amino-9-[(2,3-dihydroxypropoxy)methyl]-1,9-dihydro-
• 2-amino-9-((2,3-dihydroxypropoxy)methyl)-1H-purin-6(9H)-one
• Ganciclovir EP Impurity E (iso-Ganciclovir)
• Iso Ganciclovir
• 2-amino-9-(2,3-dihydroxypropoxymethyl)-3H-purin-6-one
• 2-AMino-9-[(2,3-dihydroxypropoxy)Methyl]-1,9-dihydro-6H-purin-6-one
• Ganciclovir EP impurity E

Ganciclovir Related Compound A ((RS)-2-Amino-9-(2,3-dihydroxy-propoxymethyl)-1,9-dihydro-purin-6-one)

CAS: 86357-09-7

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, nesoi

Formula: C₉H₁₃N₅O₄

Color and Shape: White Off-White Powder

Molecular weight: 255.24

Ref: 45-1288317

Ganciclovir EP Impurity E (Ganciclovir USP Related Compound A, Iso-Ganciclovir)

CAS: 86357-09-7

Formula: C₉H₁₃N₅O₄

Color and Shape: White To Off-White Solid

Molecular weight: 255.23

Ref: 4Z-G-168

Ganciclovir EP Impurity E

CAS: 86357-09-7

Formula: C₉H₁₃N₅O₄

Molecular weight: 255.23

Ref: ST-EA-CP-G5005

Iso Ganciclovir

Controlled Product

CAS: 86357-09-7

Formula: C₉H₁₃N₅O₄

Color and Shape: Neat

Molecular weight: 255.23

Ref: TR-I818750

IsoGanciclovir

CAS: 86357-09-7

IsoGanciclovir is a prodrug that is converted to ganciclovir in the body. It has antiviral activity against herpesviruses, such as cytomegalovirus and varicella-zoster virus. Ganciclovir inhibits viral replication by interfering with the synthesis of DNA and RNA. IsoGanciclovir is synthesized from glycerol and moieties with an acetyl group on the sugar moiety. The synthesis proceeds through a 1,3-dipolar cycloaddition between glycerol and methoxymethyl ethers followed by a Diels-Alder reaction between the resulting diene and maleimide. The synthesis of IsoGanciclovir can be used for preparative purposes, such as for synthesizing other antiviral drugs or nucleosides.

Formula: C₉H₁₃N₅O₄

Purity: Min. 95%

Molecular weight: 255.23 g/mol

Ref: 3D-FG23645