CAS 86361-68-4
:(17alpha)-6-fluorocholest-5-en-3-ol
Description:
(17alpha)-6-Fluorocholest-5-en-3-ol, with the CAS number 86361-68-4, is a synthetic derivative of cholesterol, characterized by the presence of a fluorine atom at the 6-position and a double bond between the 5 and 6 positions of the steroid nucleus. This compound exhibits a steroidal structure, which is typical of cholesterol derivatives, and is known for its potential biological activity, particularly in the context of pharmacology and biochemistry. The fluorine substitution can influence the compound's lipophilicity, receptor binding affinity, and metabolic stability, making it of interest in medicinal chemistry. Its hydroxyl group at the 3-position contributes to its polar characteristics, which can affect its solubility and interaction with biological membranes. Overall, (17alpha)-6-fluorocholest-5-en-3-ol serves as a valuable compound for research into cholesterol metabolism, steroid hormone synthesis, and the development of therapeutic agents targeting cholesterol-related pathways.
Formula:C27H45FO
InChI:InChI=1/C27H45FO/c1-17(2)7-6-8-18(3)21-9-10-22-20-16-25(28)24-15-19(29)11-13-27(24,5)23(20)12-14-26(21,22)4/h17-23,29H,6-16H2,1-5H3/t18-,19?,20+,21+,22+,23+,26-,27-/m1/s1
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Found 1 products.
(17α)-6-Fluorocholest-5-en-3-ol
CAS:Controlled Product<p>(17alpha)-6-Fluorocholest-5-en-3-ol is a fluorinated cholesterol derivative that inhibits the cholesterol acyltransferase enzyme, which is responsible for the enzymatic esterification of cholesterol to form cholesteryl esters. This product has been shown to inhibit cellular growth and may be useful in treating bacterial infections. (17alpha)-6-Fluorocholest-5-en-3-ol has also been shown to inhibit the growth of bacteria by binding to the hmg coa reductase enzyme, which is involved in cholesterol metabolism. This product has been found to increase membrane fluidity and promote cell growth. It also prevents the formation of foam cells by inhibiting cholesterol uptake from peripheral tissues into macrophages.</p>Formula:C27H45FOPurity:Min. 95%Molecular weight:404.64 g/mol
