CAS 863884-77-9

BI 207127

Description:

BI 207127, with the CAS number 863884-77-9, is a chemical compound that has been studied primarily for its potential therapeutic applications. It is classified as a small molecule and is known to act as a selective inhibitor of certain biological pathways, particularly those involved in inflammatory processes. The compound exhibits a specific mechanism of action that targets particular enzymes or receptors, which may contribute to its efficacy in treating conditions related to inflammation or immune response. In terms of its physical and chemical properties, BI 207127 is typically characterized by its molecular structure, solubility, and stability under various conditions. Safety and toxicity profiles are also crucial, as they determine the compound's suitability for clinical use. Research on BI 207127 may include pharmacokinetics, pharmacodynamics, and potential side effects, which are essential for understanding its overall therapeutic potential. As with any investigational compound, ongoing studies are necessary to fully elucidate its characteristics and applications in medicine.

Formula: C₃₄H₃₃BrN₆O₃

InChI: InChI=1S/C34H33BrN6O3/c1-40-26-17-22(10-11-24(26)29(21-6-3-4-7-21)30(40)31-36-18-23(35)19-37-31)32(44)39-34(14-5-15-34)33-38-25-12-8-20(9-13-28(42)43)16-27(25)41(33)2/h8-13,16-19,21H,3-7,14-15H2,1-2H3,(H,39,44)(H,42,43)/b13-9+

InChI key: InChIKey=BMAIGAHXAJEULY-UKTHLTGXSA-N

SMILES: CN1C(=C(C=2C1=CC(C(NC3(CCC3)C=4N(C)C=5C(N4)=CC=C(/C=C/C(O)=O)C5)=O)=CC2)C6CCCC6)C=7N=CC(Br)=CN7

Synonyms:

• BI 207127
• Deleobuvir
• (2E)-3-[2-[1-[[[2-(5-Bromo-2-pyrimidinyl)-3-cyclopentyl-1-methyl-1H-indol-6-yl]carbonyl]amino]cyclobutyl]-1-methyl-1H-benzimidazol-6-yl]-2-propenoic acid
• 2-Propenoic acid, 3-[2-[1-[[[2-(5-bromo-2-pyrimidinyl)-3-cyclopentyl-1-methyl-1H-indol-6-yl]carbonyl]amino]cyclobutyl]-1-methyl-1H-benzimidazol-6-yl]-, (2E)-
• (E)-3-[2-[1-[[[2-(5-Bromopyrimidin-2-yl)-3-cyclopentyl-1-methyl-1H-indol-6-yl]carbonyl]amino]cyclobutyl]-1-methyl-1H-benzimidazol-6-yl]-2-propenoic acid

Deleobuvir

CAS: 863884-77-9

Deleobuvir is a potent and selective inhibitor of the Kv1.3 voltage-gated potassium channel, which is activated in response to membrane depolarization. Deleobuvir inhibits the activation of this channel by blocking the binding of its activator peptide, Kv1.3-activating peptide (KAP). Deleobuvir has been shown to be effective in inhibiting the growth of cells that express this receptor, such as tumor cells.

Formula: C₃₄H₃₃BrN₆O₃

Purity: Min. 95%

Molecular weight: 653.6 g/mol

Ref: 3D-NJB88477

Deleobuvir

CAS: 863884-77-9

Deleobuvir(BI207127) is an inhibitor of non-nucleoside hepatitis C virus NS5B polymerase for the treatment of hepatitis C.

Formula: C₃₄H₃₃BrN₆O₃

Color and Shape: Solid

Molecular weight: 653.57

Ref: TM-T31369