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CAS 86393-37-5

:

Amifloxacin

Description:
Amifloxacin is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily effective against a variety of Gram-positive and Gram-negative bacteria, making it useful in treating various infections. The chemical structure of Amifloxacin includes a bicyclic core with a fluorine atom, which enhances its potency and bioavailability. It exhibits a mechanism of action that involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. Amifloxacin is typically administered orally and is known for its favorable pharmacokinetic properties, including good absorption and distribution in tissues. Additionally, it has a relatively low incidence of side effects compared to other antibiotics, although potential adverse reactions can include gastrointestinal disturbances and, in rare cases, effects on the central nervous system. As with all antibiotics, the emergence of resistance is a concern, necessitating careful use and adherence to prescribed regimens. Overall, Amifloxacin represents an important option in the arsenal against bacterial infections.
Formula:C16H19FN4O3
InChI:InChI=1/C16H19FN4O3/c1-18-21-9-11(16(23)24)15(22)10-7-12(17)14(8-13(10)21)20-5-3-19(2)4-6-20/h7-9,18H,3-6H2,1-2H3,(H,23,24)
InChI key:InChIKey=RUXPNBWPIRDVTH-UHFFFAOYSA-N
SMILES:N(C)N1C=2C(C(=O)C(C(O)=O)=C1)=CC(F)=C(C2)N3CCN(C)CC3
Synonyms:
  • 289-231-8
  • 3-Quinolinecarboxylic acid, 6-fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-
  • 6-Fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
  • 6-Fluoro-1-(methylamino)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • 86393-37-5
  • Win 49375
  • Amifloxacin
  • AMFX
  • Inhibitor,Win-49375,Amifloxacin,inhibit,Win 49375,Bacterial
  • amifloxacin USP/EP/BP
  • 6-Fluoro-1,4-dihydro-1-(methylamino)-7-(4-methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylic acid
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Found 6 products.