CAS 86393-37-5

Amifloxacin

Description:

Amifloxacin is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily effective against a variety of Gram-positive and Gram-negative bacteria, making it useful in treating various infections. The chemical structure of Amifloxacin includes a bicyclic core with a fluorine atom, which enhances its potency and bioavailability. It exhibits a mechanism of action that involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. Amifloxacin is typically administered orally and is known for its favorable pharmacokinetic properties, including good absorption and distribution in tissues. Additionally, it has a relatively low incidence of side effects compared to other antibiotics, although potential adverse reactions can include gastrointestinal disturbances and, in rare cases, effects on the central nervous system. As with all antibiotics, the emergence of resistance is a concern, necessitating careful use and adherence to prescribed regimens. Overall, Amifloxacin represents an important option in the arsenal against bacterial infections.

Formula: C₁₆H₁₉FN₄O₃

InChI: InChI=1/C16H19FN4O3/c1-18-21-9-11(16(23)24)15(22)10-7-12(17)14(8-13(10)21)20-5-3-19(2)4-6-20/h7-9,18H,3-6H2,1-2H3,(H,23,24)

InChI key: InChIKey=RUXPNBWPIRDVTH-UHFFFAOYSA-N

SMILES: N(C)N1C=2C(C(=O)C(C(O)=O)=C1)=CC(F)=C(C2)N3CCN(C)CC3

Synonyms:

• 289-231-8
• 3-Quinolinecarboxylic acid, 6-fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-
• 6-Fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
• 6-Fluoro-1-(methylamino)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• 86393-37-5
• Win 49375
• Amifloxacin
• AMFX
• Inhibitor,Win-49375,Amifloxacin,inhibit,Win 49375,Bacterial
• amifloxacin USP/EP/BP
• 6-Fluoro-1,4-dihydro-1-(methylamino)-7-(4-methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylic acid

3-Quinolinecarboxylicacid, 6-fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-

CAS: 86393-37-5

Formula: C₁₆H₁₉FN₄O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 334.3455

Ref: IN-DA004XD6

Amifloxacin

CAS: 86393-37-5

Formula: C₁₆H₁₉FN₄O₃

Molecular weight: 334.35

Ref: 4Z-A-213001

6-Fluoro-1-(Methylamino)-7-(4-Methylpiperazin-1-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid

CAS: 86393-37-5

6-Fluoro-1-(Methylamino)-7-(4-Methylpiperazin-1-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid

Purity: 97%

Molecular weight: 334.35g/mol

Ref: 54-PC108589

Amifloxacin

CAS: 86393-37-5

Amifloxacin

Purity: ≥98%

Molecular weight: 334.35g/mol

Ref: 54-BUP01710

Amifloxacin

CAS: 86393-37-5

Amifloxacin (Win49375) is a synthetic antibacterial compound and showed moderate activity against Staphylococcus aureus, with MICs of less than or equal to 2

Formula: C₁₆H₁₉FN₄O₃

Purity: 99.89%

Color and Shape: Solid

Molecular weight: 334.35

Ref: TM-T17254

Amifloxacin

CAS: 86393-37-5

Purity: 97%

Molecular weight: 334.351

Ref: 10-F979286