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CAS 864070-44-0

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Empagliflozin

Description:
Empagliflozin is a medication primarily used in the management of type 2 diabetes mellitus. It belongs to the class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors, which function by preventing the reabsorption of glucose in the kidneys, thereby promoting its excretion in urine and lowering blood glucose levels. The chemical formula of empagliflozin reflects its complex structure, which includes a glucose moiety linked to a substituted aromatic ring. This compound exhibits a high degree of selectivity for the SGLT2 transporter, making it effective in reducing hyperglycemia. Additionally, empagliflozin has been associated with cardiovascular benefits and weight loss in patients with diabetes. Its pharmacokinetics indicate good oral bioavailability, with a relatively long half-life, allowing for once-daily dosing. Common side effects may include urinary tract infections and genital mycotic infections due to increased glucose in the urine. Overall, empagliflozin represents a significant advancement in diabetes treatment, contributing to improved glycemic control and cardiovascular outcomes.
Formula:C23H27ClO7
InChI:InChI=1S/C23H27ClO7/c24-18-6-3-14(23-22(28)21(27)20(26)19(11-25)31-23)10-15(18)9-13-1-4-16(5-2-13)30-17-7-8-29-12-17/h1-6,10,17,19-23,25-28H,7-9,11-12H2/t17-,19+,20+,21-,22+,23-/m0/s1
InChI key:InChIKey=OBWASQILIWPZMG-QZMOQZSNSA-N
SMILES:O[C@H]1[C@H](C2=CC(CC3=CC=C(O[C@H]4CCOC4)C=C3)=C(Cl)C=C2)O[C@H](CO)[C@@H](O)[C@@H]1O
Synonyms:
  • (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-<span class="text-smallcaps">D</span>-glucitol
  • <span class="text-smallcaps">D</span>-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-, (1S)-
  • Bi 10773
  • D-Glucitol, 1,5-Anhydro-1-C-[4-Chloro-3-[[4-[[(3S)-Tetrahydro-3-Furanyl]Oxy]Phenyl]Methyl]Phenyl]-, (1S)-
  • Jardiance
  • Empagliflozin
  • (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol
  • D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]M ethyl]phenyl]-, (1S)-
  • (1S)-1,5-Anhydro-1-C-{4-chloro-3-[(4-{[(3S)-oxolan-3-yl]oxy}phenyl)methyl]phenyl}-D-glucitol
  • Boehringer Ingelheim(BI-44847)
  • See more synonyms
Found 17 products.